Detection of hepatic metastasis from medullary thyroid cancer with Tc-99m-MIBI scintigraphy in a patient with Sipple's syndrome

Shuhei Sato, Yoshihiro Okumura, Atsuko Tamizu, Kumi Maki, Shiro Akaki, Yoshihiro Takeda, Susumu Kanazawa, Yoshio Hiraki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We report a case of Sipple's syndrome with a hepatic tumor. A 28-year-old male with medullary thyroid cancer and bilateral pheochromocytomas was diagnosed as having Sipple's syndrome. The hepatic tumor was found to be hypervascular by means of a dynamic abdominal CT scan. An I-131-MIBG scan showed no increased accumulation in the tumor. A whole body Tc-99m-MIBI scan had shown, however, increased accumulation in the tumor by 10 minutes after i.v. Tc-99m-MIBI. The hepatic tumor was diagnosed histologically as a metastasis from the medullary thyroid cancer. To our knowledge, there have been no previous reports of increased Tc-99m-MIBI accumulation in hepatic metastases from medullary thyroid cancer.

Original languageEnglish
Pages (from-to)443-446
Number of pages4
JournalAnnals of nuclear medicine
Volume15
Issue number5
DOIs
Publication statusPublished - Jan 1 2001

Keywords

  • Hepatic metastasis
  • Medullary thyroid cancer
  • Sipple's syndrome
  • Tc-99m-MIBI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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