Detection of Epstein-Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis

H. Harada, K. Iwatsuki, F. Kaneko

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

T-cell proliferative disorders are occasionally associated with Epstein- Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positive for EBV genes. Polymerase chain reaction was used to detect EBV genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations.

Original languageEnglish
Pages (from-to)379-383
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume31
Issue number2 II
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Panniculitis
Human Herpesvirus 4
Lymphoma
Epstein-Barr Virus Infections
Genes
Skin
T-Cell Lymphoma
T-Lymphocytes
Polymerase Chain Reaction
DNA

ASJC Scopus subject areas

  • Dermatology

Cite this

Detection of Epstein-Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis. / Harada, H.; Iwatsuki, K.; Kaneko, F.

In: Journal of the American Academy of Dermatology, Vol. 31, No. 2 II, 1994, p. 379-383.

Research output: Contribution to journalArticle

@article{5aa9c248f4f24a099332cdc5734600a2,
title = "Detection of Epstein-Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis",
abstract = "T-cell proliferative disorders are occasionally associated with Epstein- Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positive for EBV genes. Polymerase chain reaction was used to detect EBV genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations.",
author = "H. Harada and K. Iwatsuki and F. Kaneko",
year = "1994",
language = "English",
volume = "31",
pages = "379--383",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "2 II",

}

TY - JOUR

T1 - Detection of Epstein-Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis

AU - Harada, H.

AU - Iwatsuki, K.

AU - Kaneko, F.

PY - 1994

Y1 - 1994

N2 - T-cell proliferative disorders are occasionally associated with Epstein- Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positive for EBV genes. Polymerase chain reaction was used to detect EBV genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations.

AB - T-cell proliferative disorders are occasionally associated with Epstein- Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positive for EBV genes. Polymerase chain reaction was used to detect EBV genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations.

UR - http://www.scopus.com/inward/record.url?scp=0027984741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027984741&partnerID=8YFLogxK

M3 - Article

VL - 31

SP - 379

EP - 383

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 2 II

ER -