Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia

Jesca Nakayima, Kyoko Hayashida, Ryo Nakao, Akihiro Ishii, Hirohito Ogawa, Ichiro Nakamura, Ladslav Moonga, Bernard M. Hang'ombe, Aaron S. Mweene, Yuka Thomas, Yasuko Orba, Hirofumi Sawa, Chihiro Sugimoto

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas.

METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis.

RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%).

CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.

Original languageEnglish
Pages (from-to)490
Number of pages1
JournalParasites & vectors
Volume7
Issue number1
DOIs
Publication statusPublished - 2014
Externally publishedYes

Fingerprint Dive into the research topics of 'Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia'. Together they form a unique fingerprint.

  • Cite this

    Nakayima, J., Hayashida, K., Nakao, R., Ishii, A., Ogawa, H., Nakamura, I., Moonga, L., Hang'ombe, B. M., Mweene, A. S., Thomas, Y., Orba, Y., Sawa, H., & Sugimoto, C. (2014). Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia. Parasites & vectors, 7(1), 490. https://doi.org/10.1186/s13071-014-0490-x