Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia

Jesca Nakayima, Kyoko Hayashida, Ryo Nakao, Akihiro Ishii, Hirohito Ogawa, Ichiro Nakamura, Ladslav Moonga, Bernard M. Hang'ombe, Aaron S. Mweene, Yuka Thomas, Yasuko Orba, Hirofumi Sawa, Chihiro Sugimoto

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas.

METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis.

RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%).

CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.

Original languageEnglish
Pages (from-to)490
Number of pages1
JournalParasites & vectors
Volume7
Issue number1
DOIs
Publication statusPublished - 2014
Externally publishedYes

Fingerprint

Zambia
Zoonoses
Primates
Disease Reservoirs
Public Health Surveillance
Anaplasma phagocytophilum
Babesia
Cercopithecus aethiops
Rickettsia
Infectious Disease Transmission
Papio
Domestic Animals
Infection Control
Ecosystem
Spleen
Polymerase Chain Reaction
DNA
Population

Cite this

Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia. / Nakayima, Jesca; Hayashida, Kyoko; Nakao, Ryo; Ishii, Akihiro; Ogawa, Hirohito; Nakamura, Ichiro; Moonga, Ladslav; Hang'ombe, Bernard M.; Mweene, Aaron S.; Thomas, Yuka; Orba, Yasuko; Sawa, Hirofumi; Sugimoto, Chihiro.

In: Parasites & vectors, Vol. 7, No. 1, 2014, p. 490.

Research output: Contribution to journalArticle

Nakayima, J, Hayashida, K, Nakao, R, Ishii, A, Ogawa, H, Nakamura, I, Moonga, L, Hang'ombe, BM, Mweene, AS, Thomas, Y, Orba, Y, Sawa, H & Sugimoto, C 2014, 'Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia', Parasites & vectors, vol. 7, no. 1, pp. 490. https://doi.org/10.1186/s13071-014-0490-x
Nakayima, Jesca ; Hayashida, Kyoko ; Nakao, Ryo ; Ishii, Akihiro ; Ogawa, Hirohito ; Nakamura, Ichiro ; Moonga, Ladslav ; Hang'ombe, Bernard M. ; Mweene, Aaron S. ; Thomas, Yuka ; Orba, Yasuko ; Sawa, Hirofumi ; Sugimoto, Chihiro. / Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia. In: Parasites & vectors. 2014 ; Vol. 7, No. 1. pp. 490.
@article{aa4bc1fa12a442f19314ccdb1f174421,
title = "Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia",
abstract = "BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas.METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis.RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6{\%}), Rickettsia spp. in 35 samples (39.8{\%}) and Babesia spp. in 2 samples (2.3{\%}).CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.",
author = "Jesca Nakayima and Kyoko Hayashida and Ryo Nakao and Akihiro Ishii and Hirohito Ogawa and Ichiro Nakamura and Ladslav Moonga and Hang'ombe, {Bernard M.} and Mweene, {Aaron S.} and Yuka Thomas and Yasuko Orba and Hirofumi Sawa and Chihiro Sugimoto",
year = "2014",
doi = "10.1186/s13071-014-0490-x",
language = "English",
volume = "7",
pages = "490",
journal = "Parasites and Vectors",
issn = "1756-3305",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia

AU - Nakayima, Jesca

AU - Hayashida, Kyoko

AU - Nakao, Ryo

AU - Ishii, Akihiro

AU - Ogawa, Hirohito

AU - Nakamura, Ichiro

AU - Moonga, Ladslav

AU - Hang'ombe, Bernard M.

AU - Mweene, Aaron S.

AU - Thomas, Yuka

AU - Orba, Yasuko

AU - Sawa, Hirofumi

AU - Sugimoto, Chihiro

PY - 2014

Y1 - 2014

N2 - BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas.METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis.RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%).CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.

AB - BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas.METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis.RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%).CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.

UR - http://www.scopus.com/inward/record.url?scp=84964696698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964696698&partnerID=8YFLogxK

U2 - 10.1186/s13071-014-0490-x

DO - 10.1186/s13071-014-0490-x

M3 - Article

VL - 7

SP - 490

JO - Parasites and Vectors

JF - Parasites and Vectors

SN - 1756-3305

IS - 1

ER -