Abstract
A series of imidazolium salt derivatives was prepared as part of a search for subtype-selective antimuscarinic agents. On the basis of measurements of the antimuscarinic activity and subtype-selectivity for M2 and M3 muscarinic receptors, the structure-activity relationships of these compounds are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 3003-3008 |
| Number of pages | 6 |
| Journal | Bioorganic and Medicinal Chemistry Letters |
| Volume | 9 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - Oct 18 1999 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry
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Cite this
Miyachi, H., Kiyota, H., & Segawa, M. (1999). Design, synthesis and antimuscarinic activity of some imidazolium derivatives. Bioorganic and Medicinal Chemistry Letters, 9(20), 3003-3008. https://doi.org/10.1016/S0960-894X(99)00517-X