Design and synthesis of phthalimide-based fluorescent liver X receptor antagonists

Kenji Kishida, Atsushi Aoyama, Yuichi Hashimoto, Hiroyuki Miyachi

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Based on our structure-activity relationship study of liver X receptor (LXR) ligands, we designed and synthesized fluorescent LXR antagonists containing an unsubstituted or substituted amino group on a phthalimide unit.

Original languageEnglish
Pages (from-to)1524-1528
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume58
Issue number11
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Fluorescent ligand
  • Liver X receptor
  • Liver X receptor antagonist

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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