Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses

Hideo Tanaka; Masatoshi Taniguchi; Yutaka Kameyama; Sigeru Torii; Michio Sasaoka; Takashi Shiroi; Ryo Kikuchi; Ichiro Kawahara; Akihiro Shimabayashi; Sigemitsu Nagao

doi:10.1016/S0040-4039(00)97140-5

Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses

Hideo Tanaka, Masatoshi Taniguchi, Yutaka Kameyama, Sigeru Torii, Michio Sasaoka, Takashi Shiroi, Ryo Kikuchi, Ichiro Kawahara, Akihiro Shimabayashi, Sigemitsu Nagao

Faculty of Engineering

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Deprotection of p-methoxybenzyl, diphenylmethyl, and tert-butyl ester groups, which is an essential step of β-lactam antibiotic synthesis, can be performed successfully by gentle heating in phenolic media.

Original language	English
Pages (from-to)	6661-6662
Number of pages	2
Journal	Tetrahedron Letters
Volume	31
Issue number	46
DOIs	https://doi.org/10.1016/S0040-4039(00)97140-5
Publication status	Published - 1990

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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Tanaka, H, Taniguchi, M, Kameyama, Y, Torii, S, Sasaoka, M, Shiroi, T, Kikuchi, R, Kawahara, I, Shimabayashi, A & Nagao, S 1990, 'Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses', Tetrahedron Letters, vol. 31, no. 46, pp. 6661-6662. https://doi.org/10.1016/S0040-4039(00)97140-5

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title = "Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses",

abstract = "Deprotection of p-methoxybenzyl, diphenylmethyl, and tert-butyl ester groups, which is an essential step of β-lactam antibiotic synthesis, can be performed successfully by gentle heating in phenolic media.",

author = "Hideo Tanaka and Masatoshi Taniguchi and Yutaka Kameyama and Sigeru Torii and Michio Sasaoka and Takashi Shiroi and Ryo Kikuchi and Ichiro Kawahara and Akihiro Shimabayashi and Sigemitsu Nagao",

year = "1990",

doi = "10.1016/S0040-4039(00)97140-5",

language = "English",

volume = "31",

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journal = "Tetrahedron Letters",

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T1 - Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses

AU - Tanaka, Hideo

AU - Taniguchi, Masatoshi

AU - Kameyama, Yutaka

AU - Torii, Sigeru

AU - Sasaoka, Michio

AU - Shiroi, Takashi

AU - Kikuchi, Ryo

AU - Kawahara, Ichiro

AU - Shimabayashi, Akihiro

AU - Nagao, Sigemitsu

PY - 1990

Y1 - 1990

N2 - Deprotection of p-methoxybenzyl, diphenylmethyl, and tert-butyl ester groups, which is an essential step of β-lactam antibiotic synthesis, can be performed successfully by gentle heating in phenolic media.

AB - Deprotection of p-methoxybenzyl, diphenylmethyl, and tert-butyl ester groups, which is an essential step of β-lactam antibiotic synthesis, can be performed successfully by gentle heating in phenolic media.

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U2 - 10.1016/S0040-4039(00)97140-5

DO - 10.1016/S0040-4039(00)97140-5

M3 - Article

AN - SCOPUS:0025167349

VL - 31

SP - 6661

EP - 6662

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 46

ER -

Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses

Abstract

ASJC Scopus subject areas

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