Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses

Hideo Tanaka, Masatoshi Taniguchi, Yutaka Kameyama, Sigeru Torii, Michio Sasaoka, Takashi Shiroi, Ryo Kikuchi, Ichiro Kawahara, Akihiro Shimabayashi, Sigemitsu Nagao

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Deprotection of p-methoxybenzyl, diphenylmethyl, and tert-butyl ester groups, which is an essential step of β-lactam antibiotic synthesis, can be performed successfully by gentle heating in phenolic media.

Original languageEnglish
Pages (from-to)6661-6662
Number of pages2
JournalTetrahedron Letters
Volume31
Issue number46
DOIs
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Deprotection of carboxylic esters assisted by hydrogen bonding network in phenolic media. Its application to β-lactam antibiotic syntheses'. Together they form a unique fingerprint.

Cite this