Decreasing systolic blood pressure is associated with improving estimated glomerular filtration rate (eGFR) with lifestyle modification in Japanese healthy women

Nobuyuki Miyatake, Kenichi Shikata, Hirofumi Makino, Takeyuki Numata

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The link between changes in a subject's metabolic syndrome components and her estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese women. We used data for 53 Japanese women (46.0 ± 10.9 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant relationships between eGFR and clinical parameters at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, eGFR was significantly increased. In addition, changes in eGFR were weakly correlated with systolic blood pressure (r = -0.306, p = 0.0260). A decrease in systolic blood pressure may be associated with improving eGFR in Japanese women.

Original languageEnglish
Pages (from-to)339-343
Number of pages5
JournalActa medica Okayama
Volume64
Issue number5
Publication statusPublished - 2010

Keywords

  • Estimated glomerular filtration rate (eGFR)
  • Lifestyle modification
  • Metabolic syndrome
  • Systolic blood pressure

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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