Abstract
We have added pharmacologically inactive agent, lactose, to adjust total weight of one piece of packaged medicine to 0.3 g, when the quantity of medicine required are less than 0.3 g in the Pharmacy of Chiba University Hospital. However, it is sometimes difficult for children to ingest 0.3 g of powder. In addition, patients who need to intake several drugs simultaneously from a tube have some troubles in obstruction of the tube. On the other hand, variation in weight of packaged medicine is getting smaller due to progress of automatic powder packaging machine and the surrounding instruments. Thus we investigated whether we could decrease a total amount of packaged medicine with keeping variation of the weight within the range of specification. Weight variation of dispensed powder and loss of drug during dispensing or taking out the powder from packaging were within the range of specification even in the case of 0.2g of packaged powder, suggesting that we could decrease the total amount of powder to 0.2g without diminishing the quality. Moreover, we revealed that this change made us free from about one tenth of dilution works.
| Original language | English |
|---|---|
| Pages (from-to) | 205-210 |
| Number of pages | 6 |
| Journal | Chiba Medical Journal |
| Volume | 90 |
| Issue number | 6 |
| Publication status | Published - 2014 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Decrease in the amount of lactose as a diluent for the powder dispensing and its evaluation. / Tsukiji, Mariko; Masuda, Kazushi; Suzuki, Takaaki; Ariyoshi, Noritaka; Ishii, Itsuko.
In: Chiba Medical Journal, Vol. 90, No. 6, 2014, p. 205-210.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Decrease in the amount of lactose as a diluent for the powder dispensing and its evaluation
AU - Tsukiji, Mariko
AU - Masuda, Kazushi
AU - Suzuki, Takaaki
AU - Ariyoshi, Noritaka
AU - Ishii, Itsuko
PY - 2014
Y1 - 2014
N2 - We have added pharmacologically inactive agent, lactose, to adjust total weight of one piece of packaged medicine to 0.3 g, when the quantity of medicine required are less than 0.3 g in the Pharmacy of Chiba University Hospital. However, it is sometimes difficult for children to ingest 0.3 g of powder. In addition, patients who need to intake several drugs simultaneously from a tube have some troubles in obstruction of the tube. On the other hand, variation in weight of packaged medicine is getting smaller due to progress of automatic powder packaging machine and the surrounding instruments. Thus we investigated whether we could decrease a total amount of packaged medicine with keeping variation of the weight within the range of specification. Weight variation of dispensed powder and loss of drug during dispensing or taking out the powder from packaging were within the range of specification even in the case of 0.2g of packaged powder, suggesting that we could decrease the total amount of powder to 0.2g without diminishing the quality. Moreover, we revealed that this change made us free from about one tenth of dilution works.
AB - We have added pharmacologically inactive agent, lactose, to adjust total weight of one piece of packaged medicine to 0.3 g, when the quantity of medicine required are less than 0.3 g in the Pharmacy of Chiba University Hospital. However, it is sometimes difficult for children to ingest 0.3 g of powder. In addition, patients who need to intake several drugs simultaneously from a tube have some troubles in obstruction of the tube. On the other hand, variation in weight of packaged medicine is getting smaller due to progress of automatic powder packaging machine and the surrounding instruments. Thus we investigated whether we could decrease a total amount of packaged medicine with keeping variation of the weight within the range of specification. Weight variation of dispensed powder and loss of drug during dispensing or taking out the powder from packaging were within the range of specification even in the case of 0.2g of packaged powder, suggesting that we could decrease the total amount of powder to 0.2g without diminishing the quality. Moreover, we revealed that this change made us free from about one tenth of dilution works.
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UR - http://www.scopus.com/inward/citedby.url?scp=84923274628&partnerID=8YFLogxK
M3 - Article
VL - 90
SP - 205
EP - 210
JO - Chiba Medical Journal
JF - Chiba Medical Journal
SN - 0303-5476
IS - 6
ER -