Damage to cultivated Japanese pearl oysters by oxidative stress that was related to "mass mortality"

Yuushi Uchimura, Hirofumi Yamashita, Makoto Kuramoto, Kohji Ishihara, Manabu Sugimoto, Nobuyoshi Nakajima

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)

    Abstract

    Increased blood-DNA breakage was observed in diseased pearl oysters. They showed significant formation of 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA), whereas the oysters that had a low mortality rate from the disease had high activity of superoxide dismutase (SOD) and low amounts of 8-OHdG and MDA. These results suggest that radical damage had occurred only in the diseased pearl oysters with the cytolysis of their haemocytes, which was related to the mass mortality of the Japanese pearl oysters.

    Original languageEnglish
    Pages (from-to)2470-2473
    Number of pages4
    JournalBioscience, Biotechnology and Biochemistry
    Volume67
    Issue number11
    DOIs
    Publication statusPublished - Nov 2003

    Keywords

    • 8-hydroxydeoxyguanosine (8-OHdG)
    • Malondialdehyde (MDA)
    • Oxidative stress
    • Pearl oyster
    • Superoxide dismutase (SOD)

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry

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