Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects

Nobuyuki Miyatake, Hidetaka Nishikawa, Akie Morishita, Mie Kunitomi, Jun Wada, Hisao Suzuki, Kayo Takahashi, Hirofumi Makino, Shohei Kira, Masafumi Fujii

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Objective: It is known that the accumulation of abdominal fat is one of the risk factors for atherosclerosis. Although exercise is commonly prescribed to reduce body weight, the efficacy of low intensity exercise for the reduction of abdominal visceral adipose tissue remains to be investigated. Research design and methods: Thirty one obese Japanese males (body mass index (BMI) ≥25) ranging in age from 32 to 59, participated in a 1-year follow up study and they were instructed to have a modest increase in daily activity and record their daily walking. Before and after exercise prescription, body composition, blood pressure, physical fitness i.e. aerobic exercise level, muscle strength and flexibility were recorded. Insulin resistance was evaluated using a homeostasis model assessment, the HOMA index. Results: HOMA index, parameters of body composition, blood pressure, triglyceride and HDL cholesterol were significantly improved. The aerobic exercise level, leg strength, weight-bearing index (leg strength/body weight) and the steps taken per day were significantly increased. By stepwise multiple regression analysis, Δvisceral adipose tissue area was the major determinant for ΔHOMA index. (ΔHOMA index=-0.386+0.016 Δvisceral adipose tissue area, r2=0.267, P2=0.184, P=0.0326). Conclusions: Taken together, intra-abdominal visceral adipose tissue is critically involved in insulin resistance and daily walking rather than improvement of exercise capacity correlated with the reduction of visceral adipose tissue in obese Japanese males.

Original languageEnglish
Pages (from-to)101-107
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume58
Issue number2
DOIs
Publication statusPublished - Nov 2002

Fingerprint

Intra-Abdominal Fat
Walking
Insulin Resistance
Exercise
Abdominal Fat
Body Composition
Leg
Body Weight
Blood Pressure
Physical Fitness
Weight-Bearing
Muscle Strength
HDL Cholesterol
Prescriptions
Atherosclerosis
Triglycerides
Body Mass Index
Homeostasis
Research Design
Regression Analysis

Keywords

  • Daily waking
  • Insulin resistance
  • Visceral adipose tissue

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects. / Miyatake, Nobuyuki; Nishikawa, Hidetaka; Morishita, Akie; Kunitomi, Mie; Wada, Jun; Suzuki, Hisao; Takahashi, Kayo; Makino, Hirofumi; Kira, Shohei; Fujii, Masafumi.

In: Diabetes Research and Clinical Practice, Vol. 58, No. 2, 11.2002, p. 101-107.

Research output: Contribution to journalArticle

Miyatake, Nobuyuki ; Nishikawa, Hidetaka ; Morishita, Akie ; Kunitomi, Mie ; Wada, Jun ; Suzuki, Hisao ; Takahashi, Kayo ; Makino, Hirofumi ; Kira, Shohei ; Fujii, Masafumi. / Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects. In: Diabetes Research and Clinical Practice. 2002 ; Vol. 58, No. 2. pp. 101-107.
@article{ce831119c0e542b6be07ff21a9129fea,
title = "Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects",
abstract = "Objective: It is known that the accumulation of abdominal fat is one of the risk factors for atherosclerosis. Although exercise is commonly prescribed to reduce body weight, the efficacy of low intensity exercise for the reduction of abdominal visceral adipose tissue remains to be investigated. Research design and methods: Thirty one obese Japanese males (body mass index (BMI) ≥25) ranging in age from 32 to 59, participated in a 1-year follow up study and they were instructed to have a modest increase in daily activity and record their daily walking. Before and after exercise prescription, body composition, blood pressure, physical fitness i.e. aerobic exercise level, muscle strength and flexibility were recorded. Insulin resistance was evaluated using a homeostasis model assessment, the HOMA index. Results: HOMA index, parameters of body composition, blood pressure, triglyceride and HDL cholesterol were significantly improved. The aerobic exercise level, leg strength, weight-bearing index (leg strength/body weight) and the steps taken per day were significantly increased. By stepwise multiple regression analysis, Δvisceral adipose tissue area was the major determinant for ΔHOMA index. (ΔHOMA index=-0.386+0.016 Δvisceral adipose tissue area, r2=0.267, P2=0.184, P=0.0326). Conclusions: Taken together, intra-abdominal visceral adipose tissue is critically involved in insulin resistance and daily walking rather than improvement of exercise capacity correlated with the reduction of visceral adipose tissue in obese Japanese males.",
keywords = "Daily waking, Insulin resistance, Visceral adipose tissue",
author = "Nobuyuki Miyatake and Hidetaka Nishikawa and Akie Morishita and Mie Kunitomi and Jun Wada and Hisao Suzuki and Kayo Takahashi and Hirofumi Makino and Shohei Kira and Masafumi Fujii",
year = "2002",
month = "11",
doi = "10.1016/S0168-8227(02)00129-8",
language = "English",
volume = "58",
pages = "101--107",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Daily walking reduces visceral adipose tissue areas and improves insulin resistance in Japanese obese subjects

AU - Miyatake, Nobuyuki

AU - Nishikawa, Hidetaka

AU - Morishita, Akie

AU - Kunitomi, Mie

AU - Wada, Jun

AU - Suzuki, Hisao

AU - Takahashi, Kayo

AU - Makino, Hirofumi

AU - Kira, Shohei

AU - Fujii, Masafumi

PY - 2002/11

Y1 - 2002/11

N2 - Objective: It is known that the accumulation of abdominal fat is one of the risk factors for atherosclerosis. Although exercise is commonly prescribed to reduce body weight, the efficacy of low intensity exercise for the reduction of abdominal visceral adipose tissue remains to be investigated. Research design and methods: Thirty one obese Japanese males (body mass index (BMI) ≥25) ranging in age from 32 to 59, participated in a 1-year follow up study and they were instructed to have a modest increase in daily activity and record their daily walking. Before and after exercise prescription, body composition, blood pressure, physical fitness i.e. aerobic exercise level, muscle strength and flexibility were recorded. Insulin resistance was evaluated using a homeostasis model assessment, the HOMA index. Results: HOMA index, parameters of body composition, blood pressure, triglyceride and HDL cholesterol were significantly improved. The aerobic exercise level, leg strength, weight-bearing index (leg strength/body weight) and the steps taken per day were significantly increased. By stepwise multiple regression analysis, Δvisceral adipose tissue area was the major determinant for ΔHOMA index. (ΔHOMA index=-0.386+0.016 Δvisceral adipose tissue area, r2=0.267, P2=0.184, P=0.0326). Conclusions: Taken together, intra-abdominal visceral adipose tissue is critically involved in insulin resistance and daily walking rather than improvement of exercise capacity correlated with the reduction of visceral adipose tissue in obese Japanese males.

AB - Objective: It is known that the accumulation of abdominal fat is one of the risk factors for atherosclerosis. Although exercise is commonly prescribed to reduce body weight, the efficacy of low intensity exercise for the reduction of abdominal visceral adipose tissue remains to be investigated. Research design and methods: Thirty one obese Japanese males (body mass index (BMI) ≥25) ranging in age from 32 to 59, participated in a 1-year follow up study and they were instructed to have a modest increase in daily activity and record their daily walking. Before and after exercise prescription, body composition, blood pressure, physical fitness i.e. aerobic exercise level, muscle strength and flexibility were recorded. Insulin resistance was evaluated using a homeostasis model assessment, the HOMA index. Results: HOMA index, parameters of body composition, blood pressure, triglyceride and HDL cholesterol were significantly improved. The aerobic exercise level, leg strength, weight-bearing index (leg strength/body weight) and the steps taken per day were significantly increased. By stepwise multiple regression analysis, Δvisceral adipose tissue area was the major determinant for ΔHOMA index. (ΔHOMA index=-0.386+0.016 Δvisceral adipose tissue area, r2=0.267, P2=0.184, P=0.0326). Conclusions: Taken together, intra-abdominal visceral adipose tissue is critically involved in insulin resistance and daily walking rather than improvement of exercise capacity correlated with the reduction of visceral adipose tissue in obese Japanese males.

KW - Daily waking

KW - Insulin resistance

KW - Visceral adipose tissue

UR - http://www.scopus.com/inward/record.url?scp=0036837046&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036837046&partnerID=8YFLogxK

U2 - 10.1016/S0168-8227(02)00129-8

DO - 10.1016/S0168-8227(02)00129-8

M3 - Article

C2 - 12213351

AN - SCOPUS:0036837046

VL - 58

SP - 101

EP - 107

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

IS - 2

ER -