@article{7da64764e31144c68e715d2548fc08be,
title = "Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model",
abstract = "Cellular Therapy; Immunological Methods; Cancer",
keywords = "Cancer, Cellular Therapy, Immunological Methods",
author = "Soki Kashima and Takuya Maeda and Kyoko Masuda and Seiji Nagano and Takamitsu Inoue and Masashi Takeda and Yuka Kono and Takashi Kobayashi and Shigeyoshi Saito and Takahiro Higuchi and Hiroshi Ichise and Yuka Kobayashi and Keiko Iwaisako and Koji Terada and Yasutoshi Agata and Kazuyuki Numakura and Mitsuru Saito and Shintaro Narita and Masaki Yasukawa and Osamu Ogawa and Tomonori Habuchi and Hiroshi Kawamoto",
note = "Funding Information: We thank Izumi Shirasu, Eri Satoh, Noriyuki Utsunomiya, Takayuki Sumiyoshi, and Keiko Udaka for technical support; Dr. Fumihiko Ishikawa for kind help of material transfer; Dr. Takeshi Watanabe for critical discussion of this study; Dr. Peter Burrows (University of Alabama) for critical reading of the manuscript, and the Kyoto University Radioisotope Research Center for use of facilities. This work was supported by JSPS KAKENHI under Grant Number JP18J10676 (Grant-in-Aid for JSPS Research Fellow); by AMED under Grant Number JP19cm0106203 , JP18im0210611 , and JP19cm0106364 ; by Join Usage/Research Center program of Institute for Frontier Life and Medical Sciences, Kyoto University, Japan; by Kanae Foundation for the Promotion of Medical Science, Japan; by Bristol Myers Squibb Company Education and Research Grants 2016 under Grant Number 27447015 , Japanese branch at Japan; and by Regcell Co. Ltd., Japan. Funding Information: We thank Izumi Shirasu, Eri Satoh, Noriyuki Utsunomiya, Takayuki Sumiyoshi, and Keiko Udaka for technical support; Dr. Fumihiko Ishikawa for kind help of material transfer; Dr. Takeshi Watanabe for critical discussion of this study; Dr. Peter Burrows (University of Alabama) for critical reading of the manuscript, and the Kyoto University Radioisotope Research Center for use of facilities. This work was supported by JSPS KAKENHI under Grant Number JP18J10676 (Grant-in-Aid for JSPS Research Fellow); by AMED under Grant Number JP19cm0106203, JP18im0210611, and JP19cm0106364; by Join Usage/Research Center program of Institute for Frontier Life and Medical Sciences, Kyoto University, Japan; by Kanae Foundation for the Promotion of Medical Science, Japan; by Bristol Myers Squibb Company Education and Research Grants 2016 under Grant Number 27447015, Japanese branch at Japan; and by Regcell Co. Ltd. Japan. S.K. T.H. and H.K. conceived the project and designed the experiments. S.K. T.M. K.M. S.N. H.I. Y. Kobayashi, S.S. and K.I. performed the experiments. T.I. M.T. Y. Kono, T.K. K.T. Y.A. K.N. M.S. S.N. M.Y. and O.O. contributed to the generation of reagents and materials. S.S. and T.H. analyzed the data. S.K. K.M. and H.K. wrote the manuscript. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2020",
month = apr,
day = "24",
doi = "10.1016/j.isci.2020.100998",
language = "English",
volume = "23",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
number = "4",
}
