Cytomegalovirus retinitis in choroidal malignant lymphoma

A 62-year-old female who developed cytomegalovirus retinitis in the course of retinochoroidal malignant lymphoma initially complained of abnormal visual field and floaters, and showed retinal exudates in the left eye. She had no evidence of systemic or central nervous system malignant lymphoma. The retinal exudative lesions did not respond to corticosteroids; similar lesions appeared later in the right eye. After the third course of corticosteroid pulse therapy, she developed cytomegalovirus retinitis in the left eye. Histopathologic examination of the aqueous cells in both eyes revelaed lymphoma cells, and her basic illness was diagnosed as choroidal malignant lymphoma. The fundus lesions in both eyes degenerated after radiation therapy and intravenous ganciclovir. She later developed malignant lymphoma of the central nervous system, so was transferred to internists for systemic chemotherapy and whole brain radiation.