Cytological and immunological study of the aqueous humor in acute retinal necrosis syndrome

Toshihiko Matsuo, Tadashi Nakayama, Tetsuro Koyama, Nobuhiko Matsuo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We experienced 4 cases of acute retinal necrosis syndrome, and performed anterior chamber paracentesis as a diagnostic aid in their acute and convalescent phases. The aqueous humor obtained by it was used for measuring antibody titers to herpes group virus and electron microscopic observation. One case showed elevated titer to herpes simplex virus type 1 in the convalescent phase, while the other to varicella-zoster virus, suggesting that these 2 viruses could cause this disease. Electron microscopy showed persistent lymphocytes and macrophages throughout the course, while plasma cells appeared at the height of the inflammation corresponding to the locally elevated antibody titers. There was no electron micro-scopic evidence of viral infection in the aqueous cells examined.

Original languageEnglish
Pages (from-to)38-44
Number of pages7
JournalOphthalmologica
Volume195
Issue number1
DOIs
Publication statusPublished - 1987

Fingerprint

Acute Retinal Necrosis Syndrome
Aqueous Humor
Electrons
Viruses
Paracentesis
Human Herpesvirus 3
Antibodies
Human Herpesvirus 1
Anterior Chamber
Virus Diseases
Plasma Cells
Electron Microscopy
Macrophages
Lymphocytes
Inflammation

Keywords

  • Acute retinal necrosis syndrome
  • Antibody titer
  • Aqueous humor
  • Cytology
  • Herpes simplex virus type 1
  • Varicella-zoster virus

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Cytological and immunological study of the aqueous humor in acute retinal necrosis syndrome. / Matsuo, Toshihiko; Nakayama, Tadashi; Koyama, Tetsuro; Matsuo, Nobuhiko.

In: Ophthalmologica, Vol. 195, No. 1, 1987, p. 38-44.

Research output: Contribution to journalArticle

Matsuo, Toshihiko ; Nakayama, Tadashi ; Koyama, Tetsuro ; Matsuo, Nobuhiko. / Cytological and immunological study of the aqueous humor in acute retinal necrosis syndrome. In: Ophthalmologica. 1987 ; Vol. 195, No. 1. pp. 38-44.
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