Cytokines and chemokines: Roles in the pathophysiology and therapy of ischemia and reperfusion injury

Motoo Araki; Austin D. Schenk; Robert L. Fairchild

doi:10.1097/01.mot.0000127627.94212.76

Cytokines and chemokines: Roles in the pathophysiology and therapy of ischemia and reperfusion injury

Motoo Araki, Austin D. Schenk, Robert L. Fairchild

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

The understanding of ischemia and reperfusion injury grows, but the search for the critical early regulators of the ischemia and reperfusion injury process remains difficult. The current therapies to attenuate ischemia and reperfusion injury are overwhelming, but the subtleties of the injury and of human medicine prevent immediate clinical implementation. Cytokineand chemokine-targeted therapies to circumvent ischemia and reperfusion injury in transplanted organs hold promise for the future.

Original language	English
Pages (from-to)	139-144
Number of pages	6
Journal	Current Opinion in Organ Transplantation
Volume	9
Issue number	2
DOIs	https://doi.org/10.1097/01.mot.0000127627.94212.76
Publication status	Published - Jan 1 2004
Externally published	Yes

Keywords

Chemokines
Cytokines
Ischemia and reperfusion injury
Macrophages
Neutrophils

ASJC Scopus subject areas

Immunology and Allergy
Transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/01.mot.0000127627.94212.76

Cite this

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abstract = "The understanding of ischemia and reperfusion injury grows, but the search for the critical early regulators of the ischemia and reperfusion injury process remains difficult. The current therapies to attenuate ischemia and reperfusion injury are overwhelming, but the subtleties of the injury and of human medicine prevent immediate clinical implementation. Cytokineand chemokine-targeted therapies to circumvent ischemia and reperfusion injury in transplanted organs hold promise for the future.",

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AU - Schenk, Austin D.

AU - Fairchild, Robert L.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - The understanding of ischemia and reperfusion injury grows, but the search for the critical early regulators of the ischemia and reperfusion injury process remains difficult. The current therapies to attenuate ischemia and reperfusion injury are overwhelming, but the subtleties of the injury and of human medicine prevent immediate clinical implementation. Cytokineand chemokine-targeted therapies to circumvent ischemia and reperfusion injury in transplanted organs hold promise for the future.

AB - The understanding of ischemia and reperfusion injury grows, but the search for the critical early regulators of the ischemia and reperfusion injury process remains difficult. The current therapies to attenuate ischemia and reperfusion injury are overwhelming, but the subtleties of the injury and of human medicine prevent immediate clinical implementation. Cytokineand chemokine-targeted therapies to circumvent ischemia and reperfusion injury in transplanted organs hold promise for the future.

KW - Chemokines

KW - Cytokines

KW - Ischemia and reperfusion injury

KW - Macrophages

KW - Neutrophils

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M3 - Review article

AN - SCOPUS:35848933471

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JO - Current Opinion in Organ Transplantation

JF - Current Opinion in Organ Transplantation

IS - 2

ER -

Cytokines and chemokines: Roles in the pathophysiology and therapy of ischemia and reperfusion injury

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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