Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases

Shuko Murakami, Yasumitsu Nishimura, Megumi Maeda, Naoko Kumagai, Hiroaki Hayashi, Ying Chen, Masayasu Kusaka, Takumi Kishimoto, Takemi Otsuki

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

This review is partly composed of the presentation Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases delivered during the symposium Biological effects of fibrous and particulate substances and related areas organized by the Study Group of Fibrous and Particulate Studies of the Japanese Society of Hygiene and held at the 78th Annual Meeting in Kumamoto, Japan. In this review, we briefly introduce the results of recent immunological analysis using the plasma of silica and asbestos-exposed patients diagnosed with silicosis, pleural plaque, or malignant mesothelioma. Thereafter, experimental background and speculation concerning the immunological pathophysiology of silica and asbestos-exposed patients are discussed.

Original languageEnglish
Pages (from-to)216-222
Number of pages7
JournalEnvironmental Health and Preventive Medicine
Volume14
Issue number4
DOIs
Publication statusPublished - Jul 2009
Externally publishedYes

Keywords

  • Asbestos
  • Cytokine
  • Mesothelioma
  • Silica
  • Silicosis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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