Cytocompatibility on silicone modified with organoalkoxysilane due to emulsion polymerization

Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima

Research output: Contribution to journalConference article

Abstract

γ-Methacryloxypropyltrimethoxysilane (γ-MPS) molecules were grafted on silicone elastomer by emulsion polymerization. Fibroblast and osteoblastic cells were cultured to examine cytocompatibility of the grafted surface. A greater number of cells grew on the grafted silicone, even forming a cell layer, than on the original silicone. Moreover, the cultured cells were agglomerated on the latter though they adhered well. Thus the γ-MPS grafting was concluded to improve cytocompatibility of silicone.

Original languageEnglish
Pages (from-to)687-690
Number of pages4
JournalKey Engineering Materials
Volume240-242
Publication statusPublished - Jan 1 2003
EventProceedings of the 15th International Symposium on Ceramics in Medicine; The Annual Meeting of the International Society for Ceramics in Medicine - Sydney, NSW, Australia
Duration: Dec 4 2002Dec 8 2002

Keywords

  • Cytocompatibility
  • Emulsion polymerization
  • Silicone
  • Surface modification

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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