Cyclopropanation of electron-deficient alkenes with activated dibromomethylene compounds mediated by lithium iodide or tetrabutylammonium salts

Daisuke Kawai, Katsuaki Kawasumi, Tsukasa Miyahara, Tsunehisa Hirashita, Shuki Araki

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Reactions of electron-deficient alkenes with dibromomethylene compounds activated by cyano and ester groups were promoted by LiI or tetrabutylammonium bromide to afford the corresponding cyclopropanes in high yields.

Original languageEnglish
Pages (from-to)10390-10394
Number of pages5
JournalTetrahedron
Volume65
Issue number50
DOIs
Publication statusPublished - Dec 12 2009
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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