Abstract
Several N-3,5-dimethylphenylphthalimide analogs possessing more potent cyclooxygenase-inhibiting activity than that of aspirin were prepared during structural development studies based on thalidomide. Substituent effects on the activity were investigated.
Original language | English |
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Pages (from-to) | 1098-1102 |
Number of pages | 5 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 51 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sep 2003 |
Externally published | Yes |
Keywords
- Cyclooxygenase
- Inhibitor
- Structure-activity relationship
- Thalidomide
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery