[Cutting edge on research of cartilage metabolism. Recent progress in bio-molecular imaging of articular cartilage].

Research output: Contribution to journalArticle

Abstract

In the process of cartilage degeneration seen in osteoarthritis, loss of proteoglycan from articular cartilage has been widely accepted as a critical early event, followed by collagen degradation designated as a point of no return. Recent advance in the development of targeted molecular probes and new imaging modalities enabled the detection of qualitative and functional change of articular cartilage. In this paper, we describe the recent progress of bio-molecular imaging of articular cartilage including our fluorescent-labeled glycosaminoglycan-binding octaarginine.

Original languageEnglish
Pages (from-to)896-902
Number of pages7
JournalClinical calcium
Volume21
Issue number6
Publication statusPublished - Jun 2011

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Molecular Imaging
Articular Cartilage
Cartilage
Research
Molecular Probes
Proteoglycans
Glycosaminoglycans
Osteoarthritis
Collagen

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "In the process of cartilage degeneration seen in osteoarthritis, loss of proteoglycan from articular cartilage has been widely accepted as a critical early event, followed by collagen degradation designated as a point of no return. Recent advance in the development of targeted molecular probes and new imaging modalities enabled the detection of qualitative and functional change of articular cartilage. In this paper, we describe the recent progress of bio-molecular imaging of articular cartilage including our fluorescent-labeled glycosaminoglycan-binding octaarginine.",
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