Abstract
Epstein-Barr virus (EBV) infection is implicated in various kinds of neoplasms including certain types of cutaneous T or natural killer (NK) cell proliferative disorders. Although a pathogenic role of EBV infection is not clear, some EBV gene products expressed during a latency phase were found to have biological properties leading to cellular gene expression and immortalization. Furthermore, EBV can use an array of strategies host immune responses, and maintain the latent infection. EBV-associated cutaneous lymphoproliferative disorders are prevalent in Asia, and less frequent in western countries where infectious mononucleosis is common in adolescents and young adults. This review introduces recent advances on the mechanism of EBV infection, highlighting unique clinicopathologic manifestations of EBV-associated cutaneous lymphoproliferative disorders. Copyright (C) 2000 Elsevier Science Ireland Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 181-195 |
| Number of pages | 15 |
| Journal | Journal of Dermatological Science |
| Volume | 22 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Apr 2000 |
| Externally published | Yes |
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Keywords
- Cutaneous lymphoproliferative disorders
- Epstein-Barr virus
- Hydroa vacciniforme
- Infectious mononucleosis
- NK cell lymphoma
ASJC Scopus subject areas
- Dermatology
Cite this
Cutaneous lymphoproliferative disorders associated with Epstein-Barr virus infection : A clinical overview. / Iwatsuki, Keiji; Xu, Zigang; Ohtsuka, Mikio; Kaneko, Fumio.
In: Journal of Dermatological Science, Vol. 22, No. 3, 04.2000, p. 181-195.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cutaneous lymphoproliferative disorders associated with Epstein-Barr virus infection
T2 - A clinical overview
AU - Iwatsuki, Keiji
AU - Xu, Zigang
AU - Ohtsuka, Mikio
AU - Kaneko, Fumio
PY - 2000/4
Y1 - 2000/4
N2 - Epstein-Barr virus (EBV) infection is implicated in various kinds of neoplasms including certain types of cutaneous T or natural killer (NK) cell proliferative disorders. Although a pathogenic role of EBV infection is not clear, some EBV gene products expressed during a latency phase were found to have biological properties leading to cellular gene expression and immortalization. Furthermore, EBV can use an array of strategies host immune responses, and maintain the latent infection. EBV-associated cutaneous lymphoproliferative disorders are prevalent in Asia, and less frequent in western countries where infectious mononucleosis is common in adolescents and young adults. This review introduces recent advances on the mechanism of EBV infection, highlighting unique clinicopathologic manifestations of EBV-associated cutaneous lymphoproliferative disorders. Copyright (C) 2000 Elsevier Science Ireland Ltd.
AB - Epstein-Barr virus (EBV) infection is implicated in various kinds of neoplasms including certain types of cutaneous T or natural killer (NK) cell proliferative disorders. Although a pathogenic role of EBV infection is not clear, some EBV gene products expressed during a latency phase were found to have biological properties leading to cellular gene expression and immortalization. Furthermore, EBV can use an array of strategies host immune responses, and maintain the latent infection. EBV-associated cutaneous lymphoproliferative disorders are prevalent in Asia, and less frequent in western countries where infectious mononucleosis is common in adolescents and young adults. This review introduces recent advances on the mechanism of EBV infection, highlighting unique clinicopathologic manifestations of EBV-associated cutaneous lymphoproliferative disorders. Copyright (C) 2000 Elsevier Science Ireland Ltd.
KW - Cutaneous lymphoproliferative disorders
KW - Epstein-Barr virus
KW - Hydroa vacciniforme
KW - Infectious mononucleosis
KW - NK cell lymphoma
UR - http://www.scopus.com/inward/record.url?scp=0033956422&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033956422&partnerID=8YFLogxK
U2 - 10.1016/S0923-1811(99)00084-5
DO - 10.1016/S0923-1811(99)00084-5
M3 - Article
VL - 22
SP - 181
EP - 195
JO - Journal of Dermatological Science
JF - Journal of Dermatological Science
SN - 0923-1811
IS - 3
ER -