Current and Future Status of PET Myocardial Perfusion Tracers

Christoph Rischpler, Takahiro Higuchi, Stephan G. Nekolla

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Over the last 2 decades, positron emission tomography (PET) myocardial perfusion imaging has been proven to be highly valuable for the detection and grading of coronary artery disease. Furthermore, its diagnostic accuracy seems to outperform on single photon emission computed tomographic myocardial perfusion imaging not least because of the potential of absolute quantification of myocardial blood flow. In a clinical setting, however, the use of PET is still limited. One major hampering factor is the lack of an ideal PET perfusion tracer for daily clinical routine. This article aims to review the currently available PET myocardial perfusion tracers as well as the question if those tracers that are being developed and about to be translated into clinics have the potential to overcome this issue.

Original languageEnglish
JournalCurrent Cardiovascular Imaging Reports
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 1 2015
Externally publishedYes

Keywords

  • F-flurpiridaz
  • Myocardial perfusion imaging
  • N-ammonia
  • O-water
  • PET tracers
  • Rubidium-82

ASJC Scopus subject areas

  • Histology
  • Applied Microbiology and Biotechnology
  • Cell Biology

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