TY - JOUR
T1 - Curative treatment of cerebral arteriovenous malformations by embolisation using cellulose acetate polymer followed by surgical resection
AU - Tokunaga, Koji
AU - Kinugasa, Kazushi
AU - Meguro, Toshinari
AU - Sugiu, Kenji
AU - Nakashima, Hiroyuki
AU - Mandai, Shinya
AU - Ohmoto, Takashi
PY - 2000/1/1
Y1 - 2000/1/1
N2 - Aim: To investigate the usefulness of embolising cerebral arteriovenous malformations (AVMs) with a cellulose acetate polymer solution before surgical resection. Methods: The cases of 12 patients with AVMs treated by embolisation before surgical resection were renewed. Two types of cellulose acetate polymer solutions were used to occlude 40 feeding vessels. All patients underwent surgical resection 1-51 days after embolisation. Results: Reduction of the nidus volume after embolisation ranged from 20% to nearly 100%. Transient neurological deficits occurred in three patients, persistent deficits occurred in one and there were no haemorrhagic complications. All but one arteriovenous malformation were completely resected. Embolisation helped to identify feeding vessels and ease dissection. Histopathological examination of resected specimens disclosed mild inflammatory reactions in the acute stage and no unfavourable granulomatous changes in the chronic stage. Conclusion: Embolisation with cellulose acetate polymer solutions followed by surgical resection is safe and efficacious for treating cerebral AVMs. (C) 2000 Harcourt Publishers Ltd.
AB - Aim: To investigate the usefulness of embolising cerebral arteriovenous malformations (AVMs) with a cellulose acetate polymer solution before surgical resection. Methods: The cases of 12 patients with AVMs treated by embolisation before surgical resection were renewed. Two types of cellulose acetate polymer solutions were used to occlude 40 feeding vessels. All patients underwent surgical resection 1-51 days after embolisation. Results: Reduction of the nidus volume after embolisation ranged from 20% to nearly 100%. Transient neurological deficits occurred in three patients, persistent deficits occurred in one and there were no haemorrhagic complications. All but one arteriovenous malformation were completely resected. Embolisation helped to identify feeding vessels and ease dissection. Histopathological examination of resected specimens disclosed mild inflammatory reactions in the acute stage and no unfavourable granulomatous changes in the chronic stage. Conclusion: Embolisation with cellulose acetate polymer solutions followed by surgical resection is safe and efficacious for treating cerebral AVMs. (C) 2000 Harcourt Publishers Ltd.
KW - Cellulose acetate polymer
KW - Cerebral arteriovenous malformation
KW - Embolisation
KW - Endovascular neurosurgery
KW - Intervention neuroradiology
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U2 - 10.1054/jocn.2000.0700
DO - 10.1054/jocn.2000.0700
M3 - Article
C2 - 11013087
AN - SCOPUS:0033860126
VL - 7
SP - 1
EP - 5
JO - Journal of Clinical Neuroscience
JF - Journal of Clinical Neuroscience
SN - 0967-5868
IS - SUUP. 1
ER -