Cross-transfer effects of resistance training with blood flow restriction

Haruhiko Madarame, Mitsuo Neya, Eisuke Ochi, Koichi Nakazato, Yoshiaki Sato, Naokata Ishii

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

PURPOSE: This study investigated whether muscle hypertrophy-promoting effects are cross-transferred in resistance training with blood flow restriction, which has been shown to evoke strong endocrine activation. METHODS: Fifteen untrained men were randomly assigned into the occlusive training group (OCC, N = 8) and the normal training group (NOR, N = 7). Both groups performed the same unilateral arm exercise (arm curl) at 50% of one-repetition maximum (1RM) without occlusion (three sets, 10 repetitions). Either the dominant or nondominant arm was randomly chosen to be trained (OCC-T, NOR-T) or to serve as a control (OCC-C, NOR-C). After the arm exercise, OCC performed leg exercise with blood flow restriction (30% of 1RM, three sets, 15-30 repetitions), whereas NOR performed the same leg exercise without occlusion. The training session was performed twice a week for 10 wk. In a separate set of experiments, acute changes in blood hormone concentrations were measured after the same leg exercises with (N = 5) and without (N = 5) occlusion. RESULTS: Cross-sectional area (CSA) and isometric torque of elbow flexor muscles increased significantly in OCC-T, whereas no significant changes were observed in OCC-C, NOR-T, and NOR-C. CSA and isometric torque of thigh muscles increased significantly in OCC, whereas no significant changes were observed in NOR. Noradrenaline concentration showed a significantly larger increase after leg exercise with occlusion than after exercises without occlusion, though growth hormone and testosterone concentrations did not show significant differences between these two types of exercises. CONCLUSION: The results indicate that low-intensity resistance training increases muscular size and strength when combined with resistance exercise with blood flow restriction for other muscle groups. It was suggested that any circulating factor(s) was involved in this remote effect of exercise on muscular size.

Original languageEnglish
Pages (from-to)258-263
Number of pages6
JournalMedicine and Science in Sports and Exercise
Volume40
Issue number2
DOIs
Publication statusPublished - Feb 2008
Externally publishedYes

Fingerprint

Resistance Training
Exercise
Leg
Arm
Muscles
Torque
Elbow
Thigh
Hypertrophy
Growth Hormone
Testosterone
Norepinephrine
Hormones

Keywords

  • Growth hormone
  • Ischemia
  • Resistance exercise
  • Strength training

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

Cite this

Cross-transfer effects of resistance training with blood flow restriction. / Madarame, Haruhiko; Neya, Mitsuo; Ochi, Eisuke; Nakazato, Koichi; Sato, Yoshiaki; Ishii, Naokata.

In: Medicine and Science in Sports and Exercise, Vol. 40, No. 2, 02.2008, p. 258-263.

Research output: Contribution to journalArticle

Madarame, Haruhiko ; Neya, Mitsuo ; Ochi, Eisuke ; Nakazato, Koichi ; Sato, Yoshiaki ; Ishii, Naokata. / Cross-transfer effects of resistance training with blood flow restriction. In: Medicine and Science in Sports and Exercise. 2008 ; Vol. 40, No. 2. pp. 258-263.
@article{cbd18347dfea4120a56b0b12db131618,
title = "Cross-transfer effects of resistance training with blood flow restriction",
abstract = "PURPOSE: This study investigated whether muscle hypertrophy-promoting effects are cross-transferred in resistance training with blood flow restriction, which has been shown to evoke strong endocrine activation. METHODS: Fifteen untrained men were randomly assigned into the occlusive training group (OCC, N = 8) and the normal training group (NOR, N = 7). Both groups performed the same unilateral arm exercise (arm curl) at 50{\%} of one-repetition maximum (1RM) without occlusion (three sets, 10 repetitions). Either the dominant or nondominant arm was randomly chosen to be trained (OCC-T, NOR-T) or to serve as a control (OCC-C, NOR-C). After the arm exercise, OCC performed leg exercise with blood flow restriction (30{\%} of 1RM, three sets, 15-30 repetitions), whereas NOR performed the same leg exercise without occlusion. The training session was performed twice a week for 10 wk. In a separate set of experiments, acute changes in blood hormone concentrations were measured after the same leg exercises with (N = 5) and without (N = 5) occlusion. RESULTS: Cross-sectional area (CSA) and isometric torque of elbow flexor muscles increased significantly in OCC-T, whereas no significant changes were observed in OCC-C, NOR-T, and NOR-C. CSA and isometric torque of thigh muscles increased significantly in OCC, whereas no significant changes were observed in NOR. Noradrenaline concentration showed a significantly larger increase after leg exercise with occlusion than after exercises without occlusion, though growth hormone and testosterone concentrations did not show significant differences between these two types of exercises. CONCLUSION: The results indicate that low-intensity resistance training increases muscular size and strength when combined with resistance exercise with blood flow restriction for other muscle groups. It was suggested that any circulating factor(s) was involved in this remote effect of exercise on muscular size.",
keywords = "Growth hormone, Ischemia, Resistance exercise, Strength training",
author = "Haruhiko Madarame and Mitsuo Neya and Eisuke Ochi and Koichi Nakazato and Yoshiaki Sato and Naokata Ishii",
year = "2008",
month = "2",
doi = "10.1249/mss.0b013e31815c6d7e",
language = "English",
volume = "40",
pages = "258--263",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Cross-transfer effects of resistance training with blood flow restriction

AU - Madarame, Haruhiko

AU - Neya, Mitsuo

AU - Ochi, Eisuke

AU - Nakazato, Koichi

AU - Sato, Yoshiaki

AU - Ishii, Naokata

PY - 2008/2

Y1 - 2008/2

N2 - PURPOSE: This study investigated whether muscle hypertrophy-promoting effects are cross-transferred in resistance training with blood flow restriction, which has been shown to evoke strong endocrine activation. METHODS: Fifteen untrained men were randomly assigned into the occlusive training group (OCC, N = 8) and the normal training group (NOR, N = 7). Both groups performed the same unilateral arm exercise (arm curl) at 50% of one-repetition maximum (1RM) without occlusion (three sets, 10 repetitions). Either the dominant or nondominant arm was randomly chosen to be trained (OCC-T, NOR-T) or to serve as a control (OCC-C, NOR-C). After the arm exercise, OCC performed leg exercise with blood flow restriction (30% of 1RM, three sets, 15-30 repetitions), whereas NOR performed the same leg exercise without occlusion. The training session was performed twice a week for 10 wk. In a separate set of experiments, acute changes in blood hormone concentrations were measured after the same leg exercises with (N = 5) and without (N = 5) occlusion. RESULTS: Cross-sectional area (CSA) and isometric torque of elbow flexor muscles increased significantly in OCC-T, whereas no significant changes were observed in OCC-C, NOR-T, and NOR-C. CSA and isometric torque of thigh muscles increased significantly in OCC, whereas no significant changes were observed in NOR. Noradrenaline concentration showed a significantly larger increase after leg exercise with occlusion than after exercises without occlusion, though growth hormone and testosterone concentrations did not show significant differences between these two types of exercises. CONCLUSION: The results indicate that low-intensity resistance training increases muscular size and strength when combined with resistance exercise with blood flow restriction for other muscle groups. It was suggested that any circulating factor(s) was involved in this remote effect of exercise on muscular size.

AB - PURPOSE: This study investigated whether muscle hypertrophy-promoting effects are cross-transferred in resistance training with blood flow restriction, which has been shown to evoke strong endocrine activation. METHODS: Fifteen untrained men were randomly assigned into the occlusive training group (OCC, N = 8) and the normal training group (NOR, N = 7). Both groups performed the same unilateral arm exercise (arm curl) at 50% of one-repetition maximum (1RM) without occlusion (three sets, 10 repetitions). Either the dominant or nondominant arm was randomly chosen to be trained (OCC-T, NOR-T) or to serve as a control (OCC-C, NOR-C). After the arm exercise, OCC performed leg exercise with blood flow restriction (30% of 1RM, three sets, 15-30 repetitions), whereas NOR performed the same leg exercise without occlusion. The training session was performed twice a week for 10 wk. In a separate set of experiments, acute changes in blood hormone concentrations were measured after the same leg exercises with (N = 5) and without (N = 5) occlusion. RESULTS: Cross-sectional area (CSA) and isometric torque of elbow flexor muscles increased significantly in OCC-T, whereas no significant changes were observed in OCC-C, NOR-T, and NOR-C. CSA and isometric torque of thigh muscles increased significantly in OCC, whereas no significant changes were observed in NOR. Noradrenaline concentration showed a significantly larger increase after leg exercise with occlusion than after exercises without occlusion, though growth hormone and testosterone concentrations did not show significant differences between these two types of exercises. CONCLUSION: The results indicate that low-intensity resistance training increases muscular size and strength when combined with resistance exercise with blood flow restriction for other muscle groups. It was suggested that any circulating factor(s) was involved in this remote effect of exercise on muscular size.

KW - Growth hormone

KW - Ischemia

KW - Resistance exercise

KW - Strength training

UR - http://www.scopus.com/inward/record.url?scp=38349178404&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38349178404&partnerID=8YFLogxK

U2 - 10.1249/mss.0b013e31815c6d7e

DO - 10.1249/mss.0b013e31815c6d7e

M3 - Article

VL - 40

SP - 258

EP - 263

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 2

ER -