Crohn's disease associated with growth hormone secretory dysfunction

T. Ogura, J. Kageyama, Y. Itano, T. Yamauchi, T. Oishi, T. Aita, N. Hayakawa, T. Ogasa, K. Ota, Z. Ota, K. Hashimoto

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.

Original languageEnglish
Pages (from-to)112-117
Number of pages6
JournalInternal Medicine
Volume34
Issue number2
Publication statusPublished - 1995

Fingerprint

Crohn Disease
Growth Hormone
Human Growth Hormone
Growth
Prednisolone
Malnutrition
Intestines
Vomiting
Pathologic Constriction
Therapeutics

Keywords

  • glucocorticoid therapy
  • neurosecretory dysfunction
  • pituitary dwarfism
  • short stature

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Ogura, T., Kageyama, J., Itano, Y., Yamauchi, T., Oishi, T., Aita, T., ... Hashimoto, K. (1995). Crohn's disease associated with growth hormone secretory dysfunction. Internal Medicine, 34(2), 112-117.

Crohn's disease associated with growth hormone secretory dysfunction. / Ogura, T.; Kageyama, J.; Itano, Y.; Yamauchi, T.; Oishi, T.; Aita, T.; Hayakawa, N.; Ogasa, T.; Ota, K.; Ota, Z.; Hashimoto, K.

In: Internal Medicine, Vol. 34, No. 2, 1995, p. 112-117.

Research output: Contribution to journalArticle

Ogura, T, Kageyama, J, Itano, Y, Yamauchi, T, Oishi, T, Aita, T, Hayakawa, N, Ogasa, T, Ota, K, Ota, Z & Hashimoto, K 1995, 'Crohn's disease associated with growth hormone secretory dysfunction', Internal Medicine, vol. 34, no. 2, pp. 112-117.
Ogura T, Kageyama J, Itano Y, Yamauchi T, Oishi T, Aita T et al. Crohn's disease associated with growth hormone secretory dysfunction. Internal Medicine. 1995;34(2):112-117.
Ogura, T. ; Kageyama, J. ; Itano, Y. ; Yamauchi, T. ; Oishi, T. ; Aita, T. ; Hayakawa, N. ; Ogasa, T. ; Ota, K. ; Ota, Z. ; Hashimoto, K. / Crohn's disease associated with growth hormone secretory dysfunction. In: Internal Medicine. 1995 ; Vol. 34, No. 2. pp. 112-117.
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