Critical aortic stenosis in the first month of life: Surgical results in 26 infants

Tom R. Karl, Shunji Sano, William J. Brawn, Roger B B Mee

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Between 1980 and 1989, 26 infants aged less than 1 month underwent open aortic valvotomy for critical aortic stenosis. All had congestive heart failure requiring inotropic agents (58%), ventilation (42%), and/or prostaglandin E1 (35%) preoperatively. Nine patients with isolated aortic stenosis had an operative mortality of 0%, whereas 17 patients with other anatomical lesions had a 47% mortality (p <0.01). Univariate analysis failed to identify additional risk factors other than year of operation (p <0.05). There were four late deaths, three probably related to arrhythmia (actuarial survival at 113 months = 0.53). Two patients have required late reoperation; neither required valve replacement.

Original languageEnglish
Pages (from-to)105-109
Number of pages5
JournalAnnals of Thoracic Surgery
Volume50
Issue number1
DOIs
Publication statusPublished - 1990
Externally publishedYes

Fingerprint

Aortic Valve Stenosis
Mortality
Alprostadil
Reoperation
Ventilation
Cardiac Arrhythmias
Heart Failure
Survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Critical aortic stenosis in the first month of life : Surgical results in 26 infants. / Karl, Tom R.; Sano, Shunji; Brawn, William J.; Mee, Roger B B.

In: Annals of Thoracic Surgery, Vol. 50, No. 1, 1990, p. 105-109.

Research output: Contribution to journalArticle

Karl, Tom R. ; Sano, Shunji ; Brawn, William J. ; Mee, Roger B B. / Critical aortic stenosis in the first month of life : Surgical results in 26 infants. In: Annals of Thoracic Surgery. 1990 ; Vol. 50, No. 1. pp. 105-109.
@article{e1836f2d9c114b69b71328c0300649bc,
title = "Critical aortic stenosis in the first month of life: Surgical results in 26 infants",
abstract = "Between 1980 and 1989, 26 infants aged less than 1 month underwent open aortic valvotomy for critical aortic stenosis. All had congestive heart failure requiring inotropic agents (58{\%}), ventilation (42{\%}), and/or prostaglandin E1 (35{\%}) preoperatively. Nine patients with isolated aortic stenosis had an operative mortality of 0{\%}, whereas 17 patients with other anatomical lesions had a 47{\%} mortality (p <0.01). Univariate analysis failed to identify additional risk factors other than year of operation (p <0.05). There were four late deaths, three probably related to arrhythmia (actuarial survival at 113 months = 0.53). Two patients have required late reoperation; neither required valve replacement.",
author = "Karl, {Tom R.} and Shunji Sano and Brawn, {William J.} and Mee, {Roger B B}",
year = "1990",
doi = "10.1016/0003-4975(90)90099-R",
language = "English",
volume = "50",
pages = "105--109",
journal = "Annals of Thoracic Surgery",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "1",

}

TY - JOUR

T1 - Critical aortic stenosis in the first month of life

T2 - Surgical results in 26 infants

AU - Karl, Tom R.

AU - Sano, Shunji

AU - Brawn, William J.

AU - Mee, Roger B B

PY - 1990

Y1 - 1990

N2 - Between 1980 and 1989, 26 infants aged less than 1 month underwent open aortic valvotomy for critical aortic stenosis. All had congestive heart failure requiring inotropic agents (58%), ventilation (42%), and/or prostaglandin E1 (35%) preoperatively. Nine patients with isolated aortic stenosis had an operative mortality of 0%, whereas 17 patients with other anatomical lesions had a 47% mortality (p <0.01). Univariate analysis failed to identify additional risk factors other than year of operation (p <0.05). There were four late deaths, three probably related to arrhythmia (actuarial survival at 113 months = 0.53). Two patients have required late reoperation; neither required valve replacement.

AB - Between 1980 and 1989, 26 infants aged less than 1 month underwent open aortic valvotomy for critical aortic stenosis. All had congestive heart failure requiring inotropic agents (58%), ventilation (42%), and/or prostaglandin E1 (35%) preoperatively. Nine patients with isolated aortic stenosis had an operative mortality of 0%, whereas 17 patients with other anatomical lesions had a 47% mortality (p <0.01). Univariate analysis failed to identify additional risk factors other than year of operation (p <0.05). There were four late deaths, three probably related to arrhythmia (actuarial survival at 113 months = 0.53). Two patients have required late reoperation; neither required valve replacement.

UR - http://www.scopus.com/inward/record.url?scp=0025336999&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025336999&partnerID=8YFLogxK

U2 - 10.1016/0003-4975(90)90099-R

DO - 10.1016/0003-4975(90)90099-R

M3 - Article

C2 - 2369209

AN - SCOPUS:0025336999

VL - 50

SP - 105

EP - 109

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

SN - 0003-4975

IS - 1

ER -