Cowaniin, a C-glucosidic ellagitannin dimer linked through catechin from Cowania mexicana

Hideyuki Ito, Masateru Miyake, Eisei Nishitani, Kyoko Miyashita, Morio Yoshimura, Takashi Yoshida, Midori Takasaki, Takao Konoshima, Mutsuo Kozuka, Tsutomu Hatano

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Abstract

A new complex tannin, cowaniin (1) was isolated from the leaves and stems of Cowania mexicana (Rosaceae), and its structure was characterized as novel C-glucosidic tannin dimer linked through (+)-catechin on the basis of spectral and chemical evidence. The inhibitory effect on activation of the Epstein-Barr virus early antigen was assessed for cowaniin. Six known polyphenols and related compounds, including a nitrile glucoside, purshianin, were also characterized.

Original languageEnglish
Pages (from-to)492-494
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume55
Issue number3
DOIs
Publication statusPublished - Mar 1 2007

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Keywords

  • C-glucosidic ellagitannin dimer
  • Complex tannin
  • Cowania mexicana
  • Cowaniin
  • Epstein-Barr virus
  • Rosaceae

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

Cite this

Ito, H., Miyake, M., Nishitani, E., Miyashita, K., Yoshimura, M., Yoshida, T., Takasaki, M., Konoshima, T., Kozuka, M., & Hatano, T. (2007). Cowaniin, a C-glucosidic ellagitannin dimer linked through catechin from Cowania mexicana. Chemical and Pharmaceutical Bulletin, 55(3), 492-494. https://doi.org/10.1248/cpb.55.492