COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma

Taku Noumi, Hiromi Watanabe, Kiichiro Ninomiya, Kadoaki Oohashi, Eiki Ichihara, Toshio Kubo, Go Makimoto, Yuka Kato, Masanori Fujii, Masahiro Tabata, Yoshinobu Maeda, Katsuyuki Hotta, Katsuyuki Kiura

Research output: Contribution to journalArticlepeer-review

Abstract

We encountered a woman with re-enlarged axillary lymph nodes during a computed tomography (CT) scan for surveillance of lung adenocarcinoma with axillary lymph node metastasis at the initial diagnosis that had shrunk with standard chemotherapy. We first suspected cancer recurrence and considered a change in the chemotherapeutic regimen. However, after careful history taking regarding the timing of her Coronavirus Disease 2019 (COVID-19) vaccination, and subsequent careful, close follow-up, radiological shrinkage suggested a strictly benign cause. Especially in lung cancer with a medical history of axillary lymph node involvement, clinicians should be aware that vaccine-associated lymphadenopathy can mimic cancer recurrence and sometimes prompt serious misjudgment regarding a current treatment course and strategy.

Original languageEnglish
Pages (from-to)593-596
Number of pages4
JournalActa medica Okayama
Volume76
Issue number5
DOIs
Publication statusPublished - 2022

Keywords

  • Axillary lymphadenopathy
  • Case report
  • Covid-19 vaccination
  • Lung cancer

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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