@article{1e21e510eae44267a579faae4e84af7a,
title = "Coupling Neuropeptide Levels to Structural Plasticity in Drosophila Clock Neurons",
abstract = "In Drosophila, core clock neurons display remarkable remodeling of their connectivity on a daily basis. In a new study, Herrero et al. investigate some of the mechanisms underlying structural plasticity and show that it relies on the activation of a novel cyclic gated nucleotide channel operating downstream of the PDFR signaling pathway.",
keywords = "CNGA, LNvs, PDF, activity-dependent synaptic plasticity, circadian remodeling, lLNvs, sLNvs, structural plasticity",
author = "Anastasia Herrero and Taishi Yoshii and Ispizua, {Juan Ignacio} and Carina Colque and Veenstra, {Jan A.} and Muraro, {Nara I.} and Ceriani, {Mar{\'i}a Fernanda}",
note = "Funding Information: We are indebted to Milena Damulewicz and members of the Ceriani lab for critical discussion and to Sofia Polcow{\~n}uk for help with statistical analysis. We thank the Bloomington Stock Center (USA) and Vienna Drosophila Resource Center for fly stocks. We are particularly grateful to Fundaci{\'o}n Williams (Buenos Aires, Argentina) for their generous contribution. M.F.C. and N.I.M. are members of the National Research Council for Science and Technology (CONICET). A.H. and J.I.I. are/were recipients of fellowships from CONICET . This work was supported by grants from ANPCyT Argentina ( PICT2011-2185 and PICT2015-2041 to M.F.C. and PICT2011-2364 to N.I.M.), the JSPS ( KAKENHI 15H05600 ) to T.Y., by a FIRCA-NIH grant ( 1R03TW008342 ) to M.F.C., and by FOCEM-Mercosur ( COF 03/11 ) to IBioBA. Funding Information: We are indebted to Milena Damulewicz and members of the Ceriani lab for critical discussion and to Sofia Polcow?uk for help with statistical analysis. We thank the Bloomington Stock Center (USA) and Vienna Drosophila Resource Center for fly stocks. We are particularly grateful to Fundaci?n Williams (Buenos Aires, Argentina) for their generous contribution. M.F.C. and N.I.M. are members of the National Research Council for Science and Technology (CONICET). A.H. and J.I.I. are/were recipients of fellowships from CONICET. This work was supported by grants from ANPCyT Argentina (PICT2011-2185 and PICT2015-2041 to M.F.C. and PICT2011-2364 to N.I.M.), the JSPS (KAKENHI 15H05600) to T.Y. by a FIRCA-NIH grant (1R03TW008342) to M.F.C. and by FOCEM-Mercosur (COF 03/11) to IBioBA. A.H. T.Y. J.I.I. C.C. and N.I.M. conducted the experiments; T.Y. and J.A.V. generated the new transgenic line; A.H. N.I.M. and M.F.C. designed the experiments; and A.H. and M.F.C. wrote the paper. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = aug,
day = "17",
doi = "10.1016/j.cub.2020.06.009",
language = "English",
volume = "30",
pages = "3154--3166.e4",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "16",
}