Coupling microreaction technologies, polymer chemistry, and processing to produce polymeric micro and nanoparticles with controlled size, morphology, and composition

Christophe A. Serra, Bruno Cortese, Ikram Ullah Khan, Nicolas Anton, Mart H.J.M. de Croon, Volker Hessel, Tsutomu Ono, Thierry Vandamme

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Polymeric micro- and nanoparticles receive the attention of researchers in different areas such as drug delivery, sensing, imaging, cosmetics, diagnostics, and biotechnology. However, processes with conventional equipment do not always allow precise control of their morphology, size, size distribution, and composition. On the other hand, microreaction technology offers improved control over the hydrodynamics, mass and heat transfer, allowing production of polymeric particles with better defined or new characteristics. Thus new horizons in polymer particle engineering arise from the use of microstructured or microfluidic devices. This article gives an insight into the latest developments and trends in the production of polymeric micro- and nanoparticles realized by microreaction technology directly.

Original languageEnglish
Pages (from-to)414-439
Number of pages26
JournalMacromolecular Reaction Engineering
Volume7
Issue number9
DOIs
Publication statusPublished - Sep 1 2013

Keywords

  • Drug delivery
  • Microfluidics
  • Microparticles
  • Microreactors
  • Nanoparticles
  • Polymers

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Polymers and Plastics

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