TY - JOUR
T1 - Coupling microreaction technologies, polymer chemistry, and processing to produce polymeric micro and nanoparticles with controlled size, morphology, and composition
AU - Serra, Christophe A.
AU - Cortese, Bruno
AU - Khan, Ikram Ullah
AU - Anton, Nicolas
AU - de Croon, Mart H.J.M.
AU - Hessel, Volker
AU - Ono, Tsutomu
AU - Vandamme, Thierry
PY - 2013/9
Y1 - 2013/9
N2 - Polymeric micro- and nanoparticles receive the attention of researchers in different areas such as drug delivery, sensing, imaging, cosmetics, diagnostics, and biotechnology. However, processes with conventional equipment do not always allow precise control of their morphology, size, size distribution, and composition. On the other hand, microreaction technology offers improved control over the hydrodynamics, mass and heat transfer, allowing production of polymeric particles with better defined or new characteristics. Thus new horizons in polymer particle engineering arise from the use of microstructured or microfluidic devices. This article gives an insight into the latest developments and trends in the production of polymeric micro- and nanoparticles realized by microreaction technology directly.
AB - Polymeric micro- and nanoparticles receive the attention of researchers in different areas such as drug delivery, sensing, imaging, cosmetics, diagnostics, and biotechnology. However, processes with conventional equipment do not always allow precise control of their morphology, size, size distribution, and composition. On the other hand, microreaction technology offers improved control over the hydrodynamics, mass and heat transfer, allowing production of polymeric particles with better defined or new characteristics. Thus new horizons in polymer particle engineering arise from the use of microstructured or microfluidic devices. This article gives an insight into the latest developments and trends in the production of polymeric micro- and nanoparticles realized by microreaction technology directly.
KW - Drug delivery
KW - Microfluidics
KW - Microparticles
KW - Microreactors
KW - Nanoparticles
KW - Polymers
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U2 - 10.1002/mren.201300101
DO - 10.1002/mren.201300101
M3 - Review article
AN - SCOPUS:84884713290
SN - 1862-832X
VL - 7
SP - 414
EP - 439
JO - Macromolecular Reaction Engineering
JF - Macromolecular Reaction Engineering
IS - 9
ER -