Corticosteroid Treatment Effective for 17 Patients with High Titers of AntiRNP Antibody

Kouzou Ookawa, Takashi Oono, Ken ichi Hatakenaka, Jiro Arata

Research output: Contribution to journalArticle


Seventeen patients with titers of RNP antibody over 1 : 10,000 seen at our clinic from 1981 to 1986 were investigated. (1) Five had systemic lupus erythematosus (SLE), 3 progressive systemic sclerosis (PSS), 7 mixed connective tissue disease (MCTD) and 2 unclassified connective tissue disease (UCTD). (2) Six of 7 with MCTD, both of 2 patients with UCTD and 1 of 3 with PSS had high titers of RNP antibody alone. (3) All 5 patients with SLE and 2 of 3 patients with PSS had both antiDNA antibody and antiSm antibody. (4) Raynaud's phenomenon was present in 12, but serious renal disease was not evident in any patient. The response to corticosteroid was positive in all patients.

Original languageEnglish
Pages (from-to)471-475
Number of pages5
JournalNishi Nihon Hifuka
Issue number3
Publication statusPublished - Jan 1 1987


ASJC Scopus subject areas

  • Dermatology

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