Correlation between ultrasound-diagnosed non-alcoholic fatty liver and periodontal condition in a cross-sectional study in Japan

Takahiro Iwasaki, Akiko Hirose, Tetsuji Azuma, Tamie Ohashi, Kazutoshi Watanabe, Akihiro Obora, Fumiko Deguchi, Takao Kojima, Atsunori Isozaki, Takaaki Tomofuji

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Abstract

This cross-sectional study investigated the relationship between periodontal condition and ultrasound-diagnosed non-alcoholic fatty liver disease (NAFLD) in a Japanese oral health check population. A total of 1226 consecutive participant were enrolled in the study. Abdominal ultrasonography was applied to diagnose NAFLD. Of the study participants, 339 (27.7%) had ultrasonography-diagnosed NAFLD. The participants with NAFLD had a significantly higher prevalence of probing pocket depth (PPD) ≥ 4 mm (86.7%) than those without NAFLD (72.9%) (p < 0.05). After adjusting for gender, age, Brinkman index, regular exercise habits, body mass index, number of teeth present, presence of periodontitis, blood pressure, and serum parameters, there was a statistically significant difference in the adjusted odds ratios of having PPD ≥ 4 mm for NAFLD (Odds ratio = 1.881, 95% confidence interval 1.184-2.987, p < 0.01). Having PPD ≥ 4 mm may be a risk factor for ultrasound-diagnosed NAFLD in this cross-sectional study of a Japanese oral health check population.

Original languageEnglish
Article number7496
JournalScientific Reports
Volume8
Issue number1
DOIs
Publication statusPublished - Dec 1 2018
Externally publishedYes

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Cite this

Iwasaki, T., Hirose, A., Azuma, T., Ohashi, T., Watanabe, K., Obora, A., Deguchi, F., Kojima, T., Isozaki, A., & Tomofuji, T. (2018). Correlation between ultrasound-diagnosed non-alcoholic fatty liver and periodontal condition in a cross-sectional study in Japan. Scientific Reports, 8(1), [7496]. https://doi.org/10.1038/s41598-018-25857-z