Coronary microcirculation in the beating heart

Fumihiko Kajiya, Toyotaka Yada, Osamu Hiramatsu, Yasuo Ogasawara, Yousuke Inai, Masahito Kajiya

Research output: Contribution to journalArticle

22 Citations (Scopus)


The phase opposition of velocity waveforms between coronary arteries (predominantly diastolic) and veins (systolic) is the most prominent characteristic of coronary hemodynamics. This unique arterial and venous flow patterns indicate the importance of intramyocardial capacitance vessels and variable resistance vessels during a cardiac cycle. It was shown that during diastole the intramyocardial capacitance vessels have two functional components, unstressed volume and ordinary capacitance. Unstressed volume is defined as the volume of blood in a vessel at zero transmural pressure. In vivo observation of systolic narrowing of arterioles in mid-wall and in subendocardium indicates the increase in resistance by cardiac contraction.

Original languageEnglish
Pages (from-to)411-419
Number of pages9
JournalMedical and Biological Engineering and Computing
Issue number5
Publication statusPublished - May 1 2008


  • Coronary capillary
  • Intramyocardial microcirculation
  • Needle-lens probe videomicroscope
  • Subendocardial flow
  • Unstressed volume

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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  • Cite this

    Kajiya, F., Yada, T., Hiramatsu, O., Ogasawara, Y., Inai, Y., & Kajiya, M. (2008). Coronary microcirculation in the beating heart. Medical and Biological Engineering and Computing, 46(5), 411-419.