Cooperative regulation of cell proliferation and differentiation by CCN2 and CCN3

Masaharu Takigawa, Harumi Kawaki, Satoshi Kubota, Karen M. Lyons, Bernard Perbal

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this chapter, we introduce a new trend in the field of CCN proteins research, that is, the yin/yang effects of CCN2 and CCN3 and the mutual regulation of ccn2 and ccn3 gene expression by these two proteins. These findings point out the need for a more thorough investigation of functional interactions between CCN proteins in normal and pathological conditions

Original languageEnglish
Title of host publicationCCN Proteins in Health and Disease: An Overview of the Fifth International Workshop on the CCN Family of Genes
PublisherSpringer Netherlands
Pages105-109
Number of pages5
ISBN (Print)9789048137787
DOIs
Publication statusPublished - 2010

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Keywords

  • CCN2/CTGF
  • CCN3/Nov
  • Chondrocytes
  • Differentiation
  • Proliferation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Takigawa, M., Kawaki, H., Kubota, S., Lyons, K. M., & Perbal, B. (2010). Cooperative regulation of cell proliferation and differentiation by CCN2 and CCN3. In CCN Proteins in Health and Disease: An Overview of the Fifth International Workshop on the CCN Family of Genes (pp. 105-109). Springer Netherlands. https://doi.org/10.1007/978-90-481-3779-4_8