Abstract
The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.
| Original language | English |
|---|---|
| Pages (from-to) | 4704-4707 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 13 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - Sep 2 2011 |
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ASJC Scopus subject areas
- Organic Chemistry
- Physical and Theoretical Chemistry
- Biochemistry
Cite this
Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C. / Takamura, Hiroyoshi; Nishiuma, Naoki; Abe, Takashi; Kadota, Isao.
In: Organic Letters, Vol. 13, No. 17, 02.09.2011, p. 4704-4707.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C
AU - Takamura, Hiroyoshi
AU - Nishiuma, Naoki
AU - Abe, Takashi
AU - Kadota, Isao
PY - 2011/9/2
Y1 - 2011/9/2
N2 - The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.
AB - The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.
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UR - http://www.scopus.com/inward/citedby.url?scp=80052250757&partnerID=8YFLogxK
U2 - 10.1021/ol2019136
DO - 10.1021/ol2019136
M3 - Article
VL - 13
SP - 4704
EP - 4707
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 17
ER -