Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C

Hiroyoshi Takamura; Naoki Nishiuma; Takashi Abe; Isao Kadota

doi:10.1021/ol2019136

Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C

Hiroyoshi Takamura, Naoki Nishiuma, Takashi Abe, Isao Kadota

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.

Original language	English
Pages (from-to)	4704-4707
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	17
DOIs	https://doi.org/10.1021/ol2019136
Publication status	Published - Sep 2 2011

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.",

author = "Hiroyoshi Takamura and Naoki Nishiuma and Takashi Abe and Isao Kadota",

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AU - Kadota, Isao

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Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C

Abstract

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