Abstract
The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.
Original language | English |
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Pages (from-to) | 4704-4707 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 13 |
Issue number | 17 |
DOIs | |
Publication status | Published - Sep 2 2011 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry