Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C

Hiroyoshi Takamura, Naoki Nishiuma, Takashi Abe, Isao Kadota

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10 Citations (Scopus)

Abstract

The HIJKLM ring system of ciguatoxin CTX3C was synthesized in a convergent manner. The key steps were a conjugate addition/alkylation sequence, spiroacetalization, intramolecular allylation, ring-closing metathesis, and hydrogenation to form the 36-α-methyl substituent.

Original languageEnglish
Pages (from-to)4704-4707
Number of pages4
JournalOrganic Letters
Volume13
Issue number17
DOIs
Publication statusPublished - Sep 2 2011

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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