Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C

Isao Kadota, Yuki Sato, Naoya Fujita, Hiroyoshi Takamura, Yoshinori Yamamoto

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

Abstract Convergent synthesis of the EFGH ring segment of ciguatoxin CTX3C was investigated by using the intramolecular allylation of an α-chloroacetoxy ether and/or O,S-acetal, and subsequent ring-closing metathesis. A new method for the preparation of γ-alkoxyallylstannane is also described.

Original languageEnglish
Article number26709
Pages (from-to)6547-6558
Number of pages12
JournalTetrahedron
Volume71
Issue number37
DOIs
Publication statusPublished - Mar 16 2015

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Allylation
Acetals
Ether
ciguatoxin 3C

Keywords

  • Ciguatoxin CTX3C
  • Convergent synthesis
  • Intramolecular allylation
  • Marine polycyclic ether
  • Ring-closing metathesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C. / Kadota, Isao; Sato, Yuki; Fujita, Naoya; Takamura, Hiroyoshi; Yamamoto, Yoshinori.

In: Tetrahedron, Vol. 71, No. 37, 26709, 16.03.2015, p. 6547-6558.

Research output: Contribution to journal › Article

Kadota, I, Sato, Y, Fujita, N, Takamura, H & Yamamoto, Y 2015, 'Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C', Tetrahedron, vol. 71, no. 37, 26709, pp. 6547-6558. https://doi.org/10.1016/j.tet.2015.04.106
Kadota I, Sato Y, Fujita N, Takamura H, Yamamoto Y. Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C. Tetrahedron. 2015 Mar 16;71(37):6547-6558. 26709. https://doi.org/10.1016/j.tet.2015.04.106
Kadota, Isao ; Sato, Yuki ; Fujita, Naoya ; Takamura, Hiroyoshi ; Yamamoto, Yoshinori. / Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C. In: Tetrahedron. 2015 ; Vol. 71, No. 37. pp. 6547-6558.
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