Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C

Isao Kadota, Yuki Sato, Naoya Fujita, Hiroyoshi Takamura, Yoshinori Yamamoto

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Abstract Convergent synthesis of the EFGH ring segment of ciguatoxin CTX3C was investigated by using the intramolecular allylation of an α-chloroacetoxy ether and/or O,S-acetal, and subsequent ring-closing metathesis. A new method for the preparation of γ-alkoxyallylstannane is also described.

Original languageEnglish
Article number26709
Pages (from-to)6547-6558
Number of pages12
JournalTetrahedron
Volume71
Issue number37
DOIs
Publication statusPublished - Aug 7 2015

Keywords

  • Ciguatoxin CTX3C
  • Convergent synthesis
  • Intramolecular allylation
  • Marine polycyclic ether
  • Ring-closing metathesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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