Convergent synthesis of the A-E ring segment of ciguatoxin CTX3C

Isao Kadota, Takashi Abe, Miyuki Uni, Hiroyoshi Takamura, Yoshinori Yamamoto

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A convergent synthesis of the A-E ring segment of ciguatoxin CTX3C was achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis.

Original languageEnglish
Pages (from-to)7784-7789
Number of pages6
JournalTetrahedron
Volume65
Issue number37
DOIs
Publication statusPublished - Sep 12 2009

Keywords

  • Ciguatoxin
  • Intramolecular allylation
  • Polycyclic ethers
  • Ring-closing metathesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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