Convenient rearrangement reaction of 2-chloroglycidic esters by PPh 3: A new synthetic method of 3-chloro-2-keto esters

Takuzo Komiyama, Yutaka Takaguchi, Sadao Tsuboi

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1 Citation (Scopus)

Abstract

A convenient rearrangement reaction of 2-chloroglycidic esters is reported. Treatment of 2-chloroglycidic esters with PPh3 under refluxing condition results in the formation of 3-chloro-2-keto esters in good to reasonable yields.

Original languageEnglish
Pages (from-to)2621-2625
Number of pages5
JournalSynthetic Communications
Volume36
Issue number18
DOIs
Publication statusPublished - Sep 1 2006

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Keywords

  • 2-Chloroglycidic ester
  • Darzens condensation
  • Dichloroacetate
  • Rearrangement reaction

ASJC Scopus subject areas

  • Organic Chemistry

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