Controlled hydrogenation of diphenylacetylene using alkylammonium formate

Hideyuki Suzuki, Ikkyu Satoh, Hiromi Nishioka, Yasuo Takeuchi

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Abstract

A simple and straightforward semihydrogenation of alkyne to alkene with triethanolamine and formic acid in the presence of PdCl2 has been described. Although hydrogenation using formic acid as a hydrogenation source has been used in combination with amines previously, few reports are available concerning the associated reactivity. We demonstrated that reactivity changes depending on the type of amine used in the hydrogenation. Further, this reaction requires no strict time control, making it a useful tool in organic synthesis.

Original languageEnglish
Pages (from-to)3834-3837
Number of pages4
JournalTetrahedron Letters
Volume58
Issue number40
DOIs
Publication statusPublished - Jan 1 2017

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Keywords

  • Amine
  • Formic acid
  • Palladium catalyst
  • Semihydrogenation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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