Contractile properties of esophageal striated muscle

Comparison with cardiac and skeletal muscles in rats

Yasutake Shimizu, Takahiko Shiina, Takeshi Shima, Kazuaki Masuda, Haruko Ogawa, Momoe Iwami, Tadashi Takewaki, Hirofumi Kuramoto

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The external muscle layer of the mammalian esophagus consists of striated muscles. We investigated the contractile properties of esophageal striated muscle by comparison with those of skeletal and cardiac muscles. Electrical field stimulation with single pulses evoked twitch-like contractile responses in esophageal muscle, similar to those in skeletal muscle in duration and similar to those in cardiac muscle in amplitude. The contractions of esophageal muscle were not affected by an inhibitor of gap junctions. Contractile responses induced by high potassium or caffeine in esophageal muscle were analogous to those in skeletal muscle. High-frequency stimulation induced a transient summation of contractions followed by sustained contractions with amplitudes similar to those of twitch-like contractions, although a large summation was observed in skeletal muscle. The results demonstrate that esophageal muscle has properties similar but not identical to those of skeletal muscle and that some specific properties may be beneficial for esophageal peristalsis.

Original languageEnglish
Article number459789
Pages (from-to)459789-459789
Number of pages1
JournalJournal of Biomedicine and Biotechnology
Volume2010
DOIs
Publication statusPublished - 2010
Externally publishedYes

Fingerprint

Striated Muscle
Muscle
Rats
Myocardium
Skeletal Muscle
Muscles
Peristalsis
Gap Junctions
Muscle Contraction
Caffeine
Electric Stimulation
Esophagus
Potassium

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Medicine
  • Genetics
  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Medicine(all)

Cite this

Contractile properties of esophageal striated muscle : Comparison with cardiac and skeletal muscles in rats. / Shimizu, Yasutake; Shiina, Takahiko; Shima, Takeshi; Masuda, Kazuaki; Ogawa, Haruko; Iwami, Momoe; Takewaki, Tadashi; Kuramoto, Hirofumi.

In: Journal of Biomedicine and Biotechnology, Vol. 2010, 459789, 2010, p. 459789-459789.

Research output: Contribution to journalArticle

Shimizu, Y, Shiina, T, Shima, T, Masuda, K, Ogawa, H, Iwami, M, Takewaki, T & Kuramoto, H 2010, 'Contractile properties of esophageal striated muscle: Comparison with cardiac and skeletal muscles in rats', Journal of Biomedicine and Biotechnology, vol. 2010, 459789, pp. 459789-459789. https://doi.org/10.1155/2010/459789
Shimizu, Yasutake ; Shiina, Takahiko ; Shima, Takeshi ; Masuda, Kazuaki ; Ogawa, Haruko ; Iwami, Momoe ; Takewaki, Tadashi ; Kuramoto, Hirofumi. / Contractile properties of esophageal striated muscle : Comparison with cardiac and skeletal muscles in rats. In: Journal of Biomedicine and Biotechnology. 2010 ; Vol. 2010. pp. 459789-459789.
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