Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase

Takemasa Matsuo, Takashi Kobayashi, Yukitaka Kimura, Asao Hosoda, Hisaji Taniguchi, Shuji Adachi

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10 Citations (Scopus)

Abstract

Glyceryl ferulate was synthesized through condensation of ferulic acid and glycerol at 50°C in glycerols with different water contents using an immobilized lipase from Candida antarctica in a batch reactor, and condensation in the glycerol with a 7.5% (w/w) water content was shown to be the favorite. The solubility of ferulic acid was higher at higher temperature in glycerol with a lower water content. The viscosity was lower at higher temperature for the glycerol with a higher water content. The condensation was carried out using a batch reactor at a temperature from 50°C to 90°C. These observations indicated that the condensation at 80°C in the glycerol with a 7.5% (w/w) water content was the most adequate for continuously synthesizing glyceryl ferulate. A reactor system was constructed for the continuous synthesis and was steadily operated to realize a productivity of 430 kg/(m3-reactor(day) without any decrease in the conversion for at least 6 days.

Original languageEnglish
Pages (from-to)375-380
Number of pages6
JournalJournal of Oleo Science
Volume57
Issue number7
Publication statusPublished - 2008
Externally publishedYes

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Keywords

  • CALB
  • Candida antarctica lipase
  • Condensation
  • Ferulic acid
  • Glyceryl ferulate

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

Cite this

Matsuo, T., Kobayashi, T., Kimura, Y., Hosoda, A., Taniguchi, H., & Adachi, S. (2008). Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase. Journal of Oleo Science, 57(7), 375-380.