Abstract
Glyceryl ferulate was synthesized through condensation of ferulic acid and glycerol at 50°C in glycerols with different water contents using an immobilized lipase from Candida antarctica in a batch reactor, and condensation in the glycerol with a 7.5% (w/w) water content was shown to be the favorite. The solubility of ferulic acid was higher at higher temperature in glycerol with a lower water content. The viscosity was lower at higher temperature for the glycerol with a higher water content. The condensation was carried out using a batch reactor at a temperature from 50°C to 90°C. These observations indicated that the condensation at 80°C in the glycerol with a 7.5% (w/w) water content was the most adequate for continuously synthesizing glyceryl ferulate. A reactor system was constructed for the continuous synthesis and was steadily operated to realize a productivity of 430 kg/(m3-reactor(day) without any decrease in the conversion for at least 6 days.
| Original language | English |
|---|---|
| Pages (from-to) | 375-380 |
| Number of pages | 6 |
| Journal | Journal of Oleo Science |
| Volume | 57 |
| Issue number | 7 |
| Publication status | Published - 2008 |
| Externally published | Yes |
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Keywords
- CALB
- Candida antarctica lipase
- Condensation
- Ferulic acid
- Glyceryl ferulate
ASJC Scopus subject areas
- Chemical Engineering(all)
- Chemistry(all)
Cite this
Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase. / Matsuo, Takemasa; Kobayashi, Takashi; Kimura, Yukitaka; Hosoda, Asao; Taniguchi, Hisaji; Adachi, Shuji.
In: Journal of Oleo Science, Vol. 57, No. 7, 2008, p. 375-380.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase
AU - Matsuo, Takemasa
AU - Kobayashi, Takashi
AU - Kimura, Yukitaka
AU - Hosoda, Asao
AU - Taniguchi, Hisaji
AU - Adachi, Shuji
PY - 2008
Y1 - 2008
N2 - Glyceryl ferulate was synthesized through condensation of ferulic acid and glycerol at 50°C in glycerols with different water contents using an immobilized lipase from Candida antarctica in a batch reactor, and condensation in the glycerol with a 7.5% (w/w) water content was shown to be the favorite. The solubility of ferulic acid was higher at higher temperature in glycerol with a lower water content. The viscosity was lower at higher temperature for the glycerol with a higher water content. The condensation was carried out using a batch reactor at a temperature from 50°C to 90°C. These observations indicated that the condensation at 80°C in the glycerol with a 7.5% (w/w) water content was the most adequate for continuously synthesizing glyceryl ferulate. A reactor system was constructed for the continuous synthesis and was steadily operated to realize a productivity of 430 kg/(m3-reactor(day) without any decrease in the conversion for at least 6 days.
AB - Glyceryl ferulate was synthesized through condensation of ferulic acid and glycerol at 50°C in glycerols with different water contents using an immobilized lipase from Candida antarctica in a batch reactor, and condensation in the glycerol with a 7.5% (w/w) water content was shown to be the favorite. The solubility of ferulic acid was higher at higher temperature in glycerol with a lower water content. The viscosity was lower at higher temperature for the glycerol with a higher water content. The condensation was carried out using a batch reactor at a temperature from 50°C to 90°C. These observations indicated that the condensation at 80°C in the glycerol with a 7.5% (w/w) water content was the most adequate for continuously synthesizing glyceryl ferulate. A reactor system was constructed for the continuous synthesis and was steadily operated to realize a productivity of 430 kg/(m3-reactor(day) without any decrease in the conversion for at least 6 days.
KW - CALB
KW - Candida antarctica lipase
KW - Condensation
KW - Ferulic acid
KW - Glyceryl ferulate
UR - http://www.scopus.com/inward/record.url?scp=45749115459&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=45749115459&partnerID=8YFLogxK
M3 - Article
C2 - 18536506
AN - SCOPUS:45749115459
VL - 57
SP - 375
EP - 380
JO - Journal of Oleo Science
JF - Journal of Oleo Science
SN - 1345-8957
IS - 7
ER -