Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature

Yayoi Yoshida, Yukitaka Kimura, Megumi Kadota, Takuo Tsuno, Shuji Adachi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90°C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90°C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90°C for at least two weeks.

Original languageEnglish
Pages (from-to)1471-1474
Number of pages4
JournalBiotechnology Letters
Volume28
Issue number18
DOIs
Publication statusPublished - Sep 1 2006
Externally publishedYes

Keywords

  • Alkyl ferulate
  • Candida antarctica lipase
  • Ferulic acid
  • Flow-type reactor

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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