Continuous positive airway pressure ameliorated severe pulmonary hypertension associated with obstructive sleep apnea

Aiko Ogawa, Tetsuro Emori, Wakako Sumita, Atsuyuki Watanabe, Hideki Fujio, Katsumasa Miyaji, Tohru Ohe

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A 52-year-old obese woman was admitted to our institution for evaluation of dyspnea and pulmonary hypertension (PH). Polysomnography revealed severe obstructive sleep apnea (OSA) with an apnea hypopnea index of 99.8. Treatment with nocturnal continuous positive airway pressure (CPAP) resulted in correction of daytime hypoxemia, hypercapnia, and near-normalization of pulmonary artery pressure. To our knowledge, this is the most severe case of OSA-associated PH (∼70 mmHg) reported to date, and it was successfully treated with nocturnal CPAP. This case demonstrates that OSA should be considered and polysomnography performed in all patients with PH, irrespective of severity, and that nocturnal CPAP has therapeutic effects on both OSA and daytime PH. Copyright

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalActa Medica Okayama
Volume60
Issue number3
Publication statusPublished - 2006

Fingerprint

Continuous Positive Airway Pressure
Obstructive Sleep Apnea
Pulmonary Hypertension
Polysomnography
Hypercapnia
Therapeutic Uses
Apnea
Dyspnea
Pulmonary Artery
Pressure
Sleep
Therapeutics

Keywords

  • Continuous positive airway pressure
  • Polysomnography
  • Secondary pulmonary hypertension
  • Sleep apnea syndrome

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Continuous positive airway pressure ameliorated severe pulmonary hypertension associated with obstructive sleep apnea. / Ogawa, Aiko; Emori, Tetsuro; Sumita, Wakako; Watanabe, Atsuyuki; Fujio, Hideki; Miyaji, Katsumasa; Ohe, Tohru.

In: Acta Medica Okayama, Vol. 60, No. 3, 2006, p. 191-195.

Research output: Contribution to journalArticle

Ogawa, A, Emori, T, Sumita, W, Watanabe, A, Fujio, H, Miyaji, K & Ohe, T 2006, 'Continuous positive airway pressure ameliorated severe pulmonary hypertension associated with obstructive sleep apnea', Acta Medica Okayama, vol. 60, no. 3, pp. 191-195.
Ogawa, Aiko ; Emori, Tetsuro ; Sumita, Wakako ; Watanabe, Atsuyuki ; Fujio, Hideki ; Miyaji, Katsumasa ; Ohe, Tohru. / Continuous positive airway pressure ameliorated severe pulmonary hypertension associated with obstructive sleep apnea. In: Acta Medica Okayama. 2006 ; Vol. 60, No. 3. pp. 191-195.
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