TY - JOUR
T1 - Contents and Uptake Rates of Mn, Fe, Co, Zn, and Se in Se-Deficient Rat Liver Cell Fractions
AU - Matsumoto, Ken Ichiro
AU - Inagaki, Tetsuya
AU - Hirunuma, Rieko
AU - Enomoto, Shuichi
AU - Endo, Kazutoyo
PY - 2001
Y1 - 2001
N2 - The contents of manganese (Mn), iron (Fe), cobalt (Co), zinc (Zn), and selenium (Se) in nuclear (NU), mitochondrial (MT), microsomal (MC), and cytosolic (CS) fractions of liver homogenates of normal and selenium-deficient (SeD) rats were determined by instrumental neutron activation analysis (INAA). The uptake rates of these elements in the liver cell fractions of both groups of rats were determined by multitracer analysis (MTA). The results indicated that Se-deficiency caused a significant increase in the content of Fe in the MC fractions. The MTA showed that the uptake rate of Fe was highest in the MC fraction, and that the uptake rate in the fraction was similar between the SeD and normal rats.
AB - The contents of manganese (Mn), iron (Fe), cobalt (Co), zinc (Zn), and selenium (Se) in nuclear (NU), mitochondrial (MT), microsomal (MC), and cytosolic (CS) fractions of liver homogenates of normal and selenium-deficient (SeD) rats were determined by instrumental neutron activation analysis (INAA). The uptake rates of these elements in the liver cell fractions of both groups of rats were determined by multitracer analysis (MTA). The results indicated that Se-deficiency caused a significant increase in the content of Fe in the MC fractions. The MTA showed that the uptake rate of Fe was highest in the MC fraction, and that the uptake rate in the fraction was similar between the SeD and normal rats.
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U2 - 10.2116/analsci.17.587
DO - 10.2116/analsci.17.587
M3 - Article
C2 - 11708137
AN - SCOPUS:0035348891
SN - 0910-6340
VL - 17
SP - 587
EP - 591
JO - Analytical Sciences
JF - Analytical Sciences
IS - 5
ER -