Construction of homoallylic alcohols from terminal alkynes and aldehydes with installation of syn-stereochemistry

Tomoya Miura, Yui Nishida, Masahiro Murakami

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A cationic rhodium(I) catalyst turns 2-silyl-1-alkenylboronate, readily prepared from a terminal alkyne, into the corresponding allylboronate species, which immediately undergoes nucleophilic addition to an aldehyde to give a syn-homoallylic alcohol stereoselectively.

Original languageEnglish
Pages (from-to)6223-6226
Number of pages4
JournalJournal of the American Chemical Society
Volume136
Issue number17
DOIs
Publication statusPublished - Apr 30 2014
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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