Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system: Synthesis of 3-norcephalosporin

Hideo Tanaka; Yoshihiko Yamaguchi; Shin Ichi Sumida; Sigeru Torii

doi:10.1039/CC9960002705

Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system: Synthesis of 3-norcephalosporin

Hideo Tanaka, Yoshihiko Yamaguchi, Shin Ichi Sumida, Sigeru Torii

Faculty of Engineering

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A sequential reductive 1,2-elimination and hydride addition process for 3,4-disubstituted butenoates derived from penicillin is successfully performed with the aid of a combination of tributyltin hydride and copper(I) chloride in N-methyl-2-pyrrolidinone (NMP) to afford 3-norcephalosporin.

Original language	English
Pages (from-to)	2705-2706
Number of pages	2
Journal	Chemical Communications
Issue number	24
DOIs	https://doi.org/10.1039/CC9960002705
Publication status	Published - Jan 1 1996

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/CC9960002705

Cite this

Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system : Synthesis of 3-norcephalosporin. / Tanaka, Hideo; Yamaguchi, Yoshihiko; Sumida, Shin Ichi; Torii, Sigeru.

In: Chemical Communications, No. 24, 01.01.1996, p. 2705-2706.

Research output: Contribution to journal › Article › peer-review

@article{ed76fabc56854f20bc092eb23e5acaf4,

title = "Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system: Synthesis of 3-norcephalosporin",

abstract = "A sequential reductive 1,2-elimination and hydride addition process for 3,4-disubstituted butenoates derived from penicillin is successfully performed with the aid of a combination of tributyltin hydride and copper(I) chloride in N-methyl-2-pyrrolidinone (NMP) to afford 3-norcephalosporin.",

author = "Hideo Tanaka and Yoshihiko Yamaguchi and Sumida, {Shin Ichi} and Sigeru Torii",

year = "1996",

month = jan,

day = "1",

doi = "10.1039/CC9960002705",

language = "English",

pages = "2705--2706",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "24",

}

TY - JOUR

T1 - Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system

T2 - Synthesis of 3-norcephalosporin

AU - Tanaka, Hideo

AU - Yamaguchi, Yoshihiko

AU - Sumida, Shin Ichi

AU - Torii, Sigeru

PY - 1996/1/1

Y1 - 1996/1/1

N2 - A sequential reductive 1,2-elimination and hydride addition process for 3,4-disubstituted butenoates derived from penicillin is successfully performed with the aid of a combination of tributyltin hydride and copper(I) chloride in N-methyl-2-pyrrolidinone (NMP) to afford 3-norcephalosporin.

AB - A sequential reductive 1,2-elimination and hydride addition process for 3,4-disubstituted butenoates derived from penicillin is successfully performed with the aid of a combination of tributyltin hydride and copper(I) chloride in N-methyl-2-pyrrolidinone (NMP) to afford 3-norcephalosporin.

UR - http://www.scopus.com/inward/record.url?scp=0030479036&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030479036&partnerID=8YFLogxK

U2 - 10.1039/CC9960002705

DO - 10.1039/CC9960002705

M3 - Article

AN - SCOPUS:0030479036

SP - 2705

EP - 2706

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 24

ER -

Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system: Synthesis of 3-norcephalosporin

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this