Abstract
A sequential reductive 1,2-elimination and hydride addition process for 3,4-disubstituted butenoates derived from penicillin is successfully performed with the aid of a combination of tributyltin hydride and copper(I) chloride in N-methyl-2-pyrrolidinone (NMP) to afford 3-norcephalosporin.
| Original language | English |
|---|---|
| Pages (from-to) | 2705-2706 |
| Number of pages | 2 |
| Journal | Chemical Communications |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - Jan 1 1996 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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Cite this
Tanaka, H., Yamaguchi, Y., Sumida, S. I., & Torii, S. (1996). Construction of cephem framework via sequential reductive 1,2-elimination-hydride addition in a tributyltin hydride-copper(I) chloride-NMP system: Synthesis of 3-norcephalosporin. Chemical Communications, (24), 2705-2706. https://doi.org/10.1039/CC9960002705