Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

Toru Kawada; Shuji Shimizu; Yusuke Sata; Atsunori Kamiya; Kenji Sunagawa; Masaru Sugimachi

doi:10.1109/IEMBS.2011.6090155

Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

Toru Kawada, Shuji Shimizu, Yusuke Sata, Atsunori Kamiya, Kenji Sunagawa, Masaru Sugimachi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

Original language	English
Title of host publication	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Pages	689-692
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2011.6090155
Publication status	Published - Dec 26 2011
Externally published	Yes
Event	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States Duration: Aug 30 2011 → Sep 3 2011

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Conference

Conference	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Country	United States
City	Boston, MA
Period	8/30/11 → 9/3/11

Fingerprint

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Cite this

Kawada, T., Shimizu, S., Sata, Y., Kamiya, A., Sunagawa, K., & Sugimachi, M. (2011). Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (pp. 689-692). [6090155] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/IEMBS.2011.6090155

Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. / Kawada, Toru; Shimizu, Shuji; Sata, Yusuke; Kamiya, Atsunori; Sunagawa, Kenji; Sugimachi, Masaru.

33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 689-692 6090155 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kawada, T, Shimizu, S, Sata, Y, Kamiya, A, Sunagawa, K & Sugimachi, M 2011, Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. in 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011., 6090155, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 689-692, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 8/30/11. https://doi.org/10.1109/IEMBS.2011.6090155

Kawada T, Shimizu S, Sata Y, Kamiya A, Sunagawa K, Sugimachi M. Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 689-692. 6090155. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/IEMBS.2011.6090155

Kawada, Toru ; Shimizu, Shuji ; Sata, Yusuke ; Kamiya, Atsunori ; Sunagawa, Kenji ; Sugimachi, Masaru. / Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats. 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. pp. 689-692 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

@inproceedings{a266e302f3b84ae9a8ff3bded87dd0a6,

title = "Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats",

abstract = "The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.",

author = "Toru Kawada and Shuji Shimizu and Yusuke Sata and Atsunori Kamiya and Kenji Sunagawa and Masaru Sugimachi",

year = "2011",

month = dec,

day = "26",

doi = "10.1109/IEMBS.2011.6090155",

language = "English",

isbn = "9781424441211",

series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

pages = "689--692",

booktitle = "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011",

note = "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 ; Conference date: 30-08-2011 Through 03-09-2011",

}

TY - GEN

T1 - Consideration on step duration to assess open-loop static characteristics of the carotid sinus baroreflex in rats

AU - Kawada, Toru

AU - Shimizu, Shuji

AU - Sata, Yusuke

AU - Kamiya, Atsunori

AU - Sunagawa, Kenji

AU - Sugimachi, Masaru

PY - 2011/12/26

Y1 - 2011/12/26

N2 - The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

AB - The carotid sinus baroreflex is one of the most important negative feedback systems to stabilize arterial pressure. Although static characteristics of the carotid sinus baroreflex can be assessed by using a stepwise input protocol under baroreflex open-loop conditions, the step duration has been determined empirically. In the present study, we examined the effects of different time windows (5-10, 15-20, 25-30, 35-40, 45-50, and 55-60 s) on the static characteristics estimated by using a 60-s stepwise input protocol in 10 anesthetized rats. Based on the results, we compared the static characteristics between actual 60-s and 20-s stepwise input protocols. Most of the parameters of the static characteristics did not differ significantly between the 60-s and 20-s stepwise input protocols, suggesting that the open-loop baroreflex static characteristics can be estimated by using a stepwise input with the step duration as short as 20 s in normal rats.

UR - http://www.scopus.com/inward/record.url?scp=84861948974&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861948974&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2011.6090155

DO - 10.1109/IEMBS.2011.6090155

M3 - Conference contribution

C2 - 22254403

AN - SCOPUS:84861948974

SN - 9781424441211

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 689

EP - 692

BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011

T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011

Y2 - 30 August 2011 through 3 September 2011

ER -

Access to Document

10.1109/IEMBS.2011.6090155