Concise synthesis of tetrahydrophenanthridone by palladium reagent

Takashi Harayama, Hiroko Toko, Hiromi Nishioka, Hitoshi Abe, Yasuo Takeuchi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Heck reaction of N-(2-halophenyl)-N-methyl-1-cyclohexene-1carboxamide (1) and 2-bromo-N-methyl-N-phenyl-1-cyclohexene-1-carboxamide (4) using a palladium reagent under several reaction conditions was examined. Reaction of 4 using Pd(OAc)2, DPPP, and Bu3P afforded tetrahydrophenanthridone (5) in excellent yield.

Original languageEnglish
Pages (from-to)541-546
Number of pages6
JournalHeterocycles
Volume59
Issue number2
Publication statusPublished - Mar 1 2003

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Palladium
cyclohexene
palladium(II) acetate

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Concise synthesis of tetrahydrophenanthridone by palladium reagent. / Harayama, Takashi; Toko, Hiroko; Nishioka, Hiromi; Abe, Hitoshi; Takeuchi, Yasuo.

In: Heterocycles, Vol. 59, No. 2, 01.03.2003, p. 541-546.

Research output: Contribution to journalArticle

Harayama, Takashi ; Toko, Hiroko ; Nishioka, Hiromi ; Abe, Hitoshi ; Takeuchi, Yasuo. / Concise synthesis of tetrahydrophenanthridone by palladium reagent. In: Heterocycles. 2003 ; Vol. 59, No. 2. pp. 541-546.
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