Abstract
Racemic compound (1) of the antimalarial agents febrifugine (d-1) was synthesized using an stereoselective Michael reaction of an ω-amidoenone (5) which was prepared by the Wittig reaction of piperidinediol (7).
Original language | English |
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Pages (from-to) | 868-869 |
Number of pages | 2 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 53 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2005 |
Keywords
- Antimalarial activity
- Febrifugine
- Stereoselective Michael reaction
- Total synthesis
- Wittig reaction
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery