Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data

Hitoshi Hayase, Koji Tokunaga, Toshio Nakayama, Kenji Sugiu, Ayumi Nishida, Seiji Arimitsu, Tomohito Hishikawa, Shigeki Ono, Makoto Ohta, Isao Date

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

BACKGROUND: There are significant differences in the postoperative morphological and hemodynamic conditions of the carotid arteries between carotid artery stenting (CAS) and endarterectomy (CEA). OBJECTIVE: To compare the postoperative rheological conditions after CAS with those after CEA with patch angioplasty (patch CEA) through the use of computational fluid dynamics (CFD) based on patient-specific data. METHODS: The rheological conditions in the carotid arteries were simulated in 2 patients after CAS and in 2 patients after patch CEA by CFD calculations. Three-dimensional reconstruction of the carotid arteries was performed with the images obtained with computed tomography angiography. The streamlines and wall shear stress (WSS) were calculated by a supercomputer. Adequate boundary conditions were determined by comparing the simulation results with ultrasound flow data. RESULTS: CFD was successfully calculated for all patients. The differences between the flow velocities of ultrasound data and those of the simulation results were limited. In the streamline analysis, the maximum flow velocities in the internal carotid artery after patch CEA were around two-thirds of those after CAS. Rotational slow flow was observed in the internal carotid artery bulb after patch CEA. WSS analysis found regional low WSS near the outer wall of the bulb. High WSS was observed at the distal end of the arteriotomy after patch CEA and at the residual stenosis after CAS. CONCLUSION: CFD of postoperative carotid arteries disclosed the differences in streamlines and WSS between CAS and patch CEA. CFD may allow us to obtain adequate rheological conditions conducive to achieving the best clinical results.

Original languageEnglish
Pages (from-to)1096-1101
Number of pages6
JournalNeurosurgery
Volume68
Issue number4
DOIs
Publication statusPublished - Apr 2011

Fingerprint

Carotid Endarterectomy
Hydrodynamics
Carotid Arteries
Endarterectomy
Internal Carotid Artery
Computed Tomography Angiography
Carotid Stenosis
Angioplasty
Hemodynamics

Keywords

  • Carotid artery
  • Computational fluid dynamics
  • Endarterectomy
  • Patch angioplasty
  • Stent

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data. / Hayase, Hitoshi; Tokunaga, Koji; Nakayama, Toshio; Sugiu, Kenji; Nishida, Ayumi; Arimitsu, Seiji; Hishikawa, Tomohito; Ono, Shigeki; Ohta, Makoto; Date, Isao.

In: Neurosurgery, Vol. 68, No. 4, 04.2011, p. 1096-1101.

Research output: Contribution to journalArticle

@article{a175054009014ea9950f138d5ef8a0a3,
title = "Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data",
abstract = "BACKGROUND: There are significant differences in the postoperative morphological and hemodynamic conditions of the carotid arteries between carotid artery stenting (CAS) and endarterectomy (CEA). OBJECTIVE: To compare the postoperative rheological conditions after CAS with those after CEA with patch angioplasty (patch CEA) through the use of computational fluid dynamics (CFD) based on patient-specific data. METHODS: The rheological conditions in the carotid arteries were simulated in 2 patients after CAS and in 2 patients after patch CEA by CFD calculations. Three-dimensional reconstruction of the carotid arteries was performed with the images obtained with computed tomography angiography. The streamlines and wall shear stress (WSS) were calculated by a supercomputer. Adequate boundary conditions were determined by comparing the simulation results with ultrasound flow data. RESULTS: CFD was successfully calculated for all patients. The differences between the flow velocities of ultrasound data and those of the simulation results were limited. In the streamline analysis, the maximum flow velocities in the internal carotid artery after patch CEA were around two-thirds of those after CAS. Rotational slow flow was observed in the internal carotid artery bulb after patch CEA. WSS analysis found regional low WSS near the outer wall of the bulb. High WSS was observed at the distal end of the arteriotomy after patch CEA and at the residual stenosis after CAS. CONCLUSION: CFD of postoperative carotid arteries disclosed the differences in streamlines and WSS between CAS and patch CEA. CFD may allow us to obtain adequate rheological conditions conducive to achieving the best clinical results.",
keywords = "Carotid artery, Computational fluid dynamics, Endarterectomy, Patch angioplasty, Stent",
author = "Hitoshi Hayase and Koji Tokunaga and Toshio Nakayama and Kenji Sugiu and Ayumi Nishida and Seiji Arimitsu and Tomohito Hishikawa and Shigeki Ono and Makoto Ohta and Isao Date",
year = "2011",
month = "4",
doi = "10.1227/NEU.0b013e318208f1a0",
language = "English",
volume = "68",
pages = "1096--1101",
journal = "Neurosurgery",
issn = "0148-396X",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data

AU - Hayase, Hitoshi

AU - Tokunaga, Koji

AU - Nakayama, Toshio

AU - Sugiu, Kenji

AU - Nishida, Ayumi

AU - Arimitsu, Seiji

AU - Hishikawa, Tomohito

AU - Ono, Shigeki

AU - Ohta, Makoto

AU - Date, Isao

PY - 2011/4

Y1 - 2011/4

N2 - BACKGROUND: There are significant differences in the postoperative morphological and hemodynamic conditions of the carotid arteries between carotid artery stenting (CAS) and endarterectomy (CEA). OBJECTIVE: To compare the postoperative rheological conditions after CAS with those after CEA with patch angioplasty (patch CEA) through the use of computational fluid dynamics (CFD) based on patient-specific data. METHODS: The rheological conditions in the carotid arteries were simulated in 2 patients after CAS and in 2 patients after patch CEA by CFD calculations. Three-dimensional reconstruction of the carotid arteries was performed with the images obtained with computed tomography angiography. The streamlines and wall shear stress (WSS) were calculated by a supercomputer. Adequate boundary conditions were determined by comparing the simulation results with ultrasound flow data. RESULTS: CFD was successfully calculated for all patients. The differences between the flow velocities of ultrasound data and those of the simulation results were limited. In the streamline analysis, the maximum flow velocities in the internal carotid artery after patch CEA were around two-thirds of those after CAS. Rotational slow flow was observed in the internal carotid artery bulb after patch CEA. WSS analysis found regional low WSS near the outer wall of the bulb. High WSS was observed at the distal end of the arteriotomy after patch CEA and at the residual stenosis after CAS. CONCLUSION: CFD of postoperative carotid arteries disclosed the differences in streamlines and WSS between CAS and patch CEA. CFD may allow us to obtain adequate rheological conditions conducive to achieving the best clinical results.

AB - BACKGROUND: There are significant differences in the postoperative morphological and hemodynamic conditions of the carotid arteries between carotid artery stenting (CAS) and endarterectomy (CEA). OBJECTIVE: To compare the postoperative rheological conditions after CAS with those after CEA with patch angioplasty (patch CEA) through the use of computational fluid dynamics (CFD) based on patient-specific data. METHODS: The rheological conditions in the carotid arteries were simulated in 2 patients after CAS and in 2 patients after patch CEA by CFD calculations. Three-dimensional reconstruction of the carotid arteries was performed with the images obtained with computed tomography angiography. The streamlines and wall shear stress (WSS) were calculated by a supercomputer. Adequate boundary conditions were determined by comparing the simulation results with ultrasound flow data. RESULTS: CFD was successfully calculated for all patients. The differences between the flow velocities of ultrasound data and those of the simulation results were limited. In the streamline analysis, the maximum flow velocities in the internal carotid artery after patch CEA were around two-thirds of those after CAS. Rotational slow flow was observed in the internal carotid artery bulb after patch CEA. WSS analysis found regional low WSS near the outer wall of the bulb. High WSS was observed at the distal end of the arteriotomy after patch CEA and at the residual stenosis after CAS. CONCLUSION: CFD of postoperative carotid arteries disclosed the differences in streamlines and WSS between CAS and patch CEA. CFD may allow us to obtain adequate rheological conditions conducive to achieving the best clinical results.

KW - Carotid artery

KW - Computational fluid dynamics

KW - Endarterectomy

KW - Patch angioplasty

KW - Stent

UR - http://www.scopus.com/inward/record.url?scp=79952901273&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952901273&partnerID=8YFLogxK

U2 - 10.1227/NEU.0b013e318208f1a0

DO - 10.1227/NEU.0b013e318208f1a0

M3 - Article

C2 - 21221041

AN - SCOPUS:79952901273

VL - 68

SP - 1096

EP - 1101

JO - Neurosurgery

JF - Neurosurgery

SN - 0148-396X

IS - 4

ER -