Comprehensive geriatric assessment in elderly breast cancer patients

Naruto Taira, Masataka Sawaki, Miyako Takahashi, Kojiro Shimozuma, Yasuo Ohashi

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Treatment of elderly patients with breast cancer is limited by the lack of evidence-based medicine due to exclusion of elderly persons from clinical studies and the difficulty of decision-making in an elderly population comprising subjects with heterogeneous health backgrounds. Individual variation of health conditions is larger in elderly patients than in young people. Since the risk-benefit balance of treatment depends on the health background, judgment of the vulnerability of individual patients is required in treatment planning. The comprehensive geriatric assessment (CGA) is a tool for acquisition of information for design of a cancer treatment plan based on evaluation of the vulnerability of elderly patients from various perspectives. The domains of the CGA include physical function, comorbidity, cognitive function, psychological status, social support system, nutrition, and medication. The CGA can be used to predict survival and adverse events; to identify health problems that cannot be detected based on medical history or examination; to recognize new problems that emerge during course observation; and to improve psychological conditions. However, application of the CGA in routine clinical practice requires establishment of a consensus regarding the survey method, evaluation scale, and use of results in decision-making. A prospective investigation of the CGA as an outcome index in elderly breast cancer patients is required to address these issues.

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalBreast Cancer
Volume17
Issue number3
DOIs
Publication statusPublished - Jul 2010

Fingerprint

Geriatric Assessment
Breast Neoplasms
Health
Decision Making
Medication Systems
Psychology
Evidence-Based Medicine
Therapeutics
Social Support
Cognition
Comorbidity
Consensus
Observation
Survival
Population
Neoplasms

Keywords

  • ADL
  • Breast cancer
  • Comprehensive geriatric assessment (CGA)
  • Elderly
  • IADL

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)
  • Medicine(all)

Cite this

Comprehensive geriatric assessment in elderly breast cancer patients. / Taira, Naruto; Sawaki, Masataka; Takahashi, Miyako; Shimozuma, Kojiro; Ohashi, Yasuo.

In: Breast Cancer, Vol. 17, No. 3, 07.2010, p. 183-189.

Research output: Contribution to journalArticle

Taira, N, Sawaki, M, Takahashi, M, Shimozuma, K & Ohashi, Y 2010, 'Comprehensive geriatric assessment in elderly breast cancer patients', Breast Cancer, vol. 17, no. 3, pp. 183-189. https://doi.org/10.1007/s12282-009-0167-z
Taira, Naruto ; Sawaki, Masataka ; Takahashi, Miyako ; Shimozuma, Kojiro ; Ohashi, Yasuo. / Comprehensive geriatric assessment in elderly breast cancer patients. In: Breast Cancer. 2010 ; Vol. 17, No. 3. pp. 183-189.
@article{bc2714b668f94f01a32fb8a5c450edbc,
title = "Comprehensive geriatric assessment in elderly breast cancer patients",
abstract = "Treatment of elderly patients with breast cancer is limited by the lack of evidence-based medicine due to exclusion of elderly persons from clinical studies and the difficulty of decision-making in an elderly population comprising subjects with heterogeneous health backgrounds. Individual variation of health conditions is larger in elderly patients than in young people. Since the risk-benefit balance of treatment depends on the health background, judgment of the vulnerability of individual patients is required in treatment planning. The comprehensive geriatric assessment (CGA) is a tool for acquisition of information for design of a cancer treatment plan based on evaluation of the vulnerability of elderly patients from various perspectives. The domains of the CGA include physical function, comorbidity, cognitive function, psychological status, social support system, nutrition, and medication. The CGA can be used to predict survival and adverse events; to identify health problems that cannot be detected based on medical history or examination; to recognize new problems that emerge during course observation; and to improve psychological conditions. However, application of the CGA in routine clinical practice requires establishment of a consensus regarding the survey method, evaluation scale, and use of results in decision-making. A prospective investigation of the CGA as an outcome index in elderly breast cancer patients is required to address these issues.",
keywords = "ADL, Breast cancer, Comprehensive geriatric assessment (CGA), Elderly, IADL",
author = "Naruto Taira and Masataka Sawaki and Miyako Takahashi and Kojiro Shimozuma and Yasuo Ohashi",
year = "2010",
month = "7",
doi = "10.1007/s12282-009-0167-z",
language = "English",
volume = "17",
pages = "183--189",
journal = "Breast Cancer",
issn = "1340-6868",
publisher = "Springer Japan",
number = "3",

}

TY - JOUR

T1 - Comprehensive geriatric assessment in elderly breast cancer patients

AU - Taira, Naruto

AU - Sawaki, Masataka

AU - Takahashi, Miyako

AU - Shimozuma, Kojiro

AU - Ohashi, Yasuo

PY - 2010/7

Y1 - 2010/7

N2 - Treatment of elderly patients with breast cancer is limited by the lack of evidence-based medicine due to exclusion of elderly persons from clinical studies and the difficulty of decision-making in an elderly population comprising subjects with heterogeneous health backgrounds. Individual variation of health conditions is larger in elderly patients than in young people. Since the risk-benefit balance of treatment depends on the health background, judgment of the vulnerability of individual patients is required in treatment planning. The comprehensive geriatric assessment (CGA) is a tool for acquisition of information for design of a cancer treatment plan based on evaluation of the vulnerability of elderly patients from various perspectives. The domains of the CGA include physical function, comorbidity, cognitive function, psychological status, social support system, nutrition, and medication. The CGA can be used to predict survival and adverse events; to identify health problems that cannot be detected based on medical history or examination; to recognize new problems that emerge during course observation; and to improve psychological conditions. However, application of the CGA in routine clinical practice requires establishment of a consensus regarding the survey method, evaluation scale, and use of results in decision-making. A prospective investigation of the CGA as an outcome index in elderly breast cancer patients is required to address these issues.

AB - Treatment of elderly patients with breast cancer is limited by the lack of evidence-based medicine due to exclusion of elderly persons from clinical studies and the difficulty of decision-making in an elderly population comprising subjects with heterogeneous health backgrounds. Individual variation of health conditions is larger in elderly patients than in young people. Since the risk-benefit balance of treatment depends on the health background, judgment of the vulnerability of individual patients is required in treatment planning. The comprehensive geriatric assessment (CGA) is a tool for acquisition of information for design of a cancer treatment plan based on evaluation of the vulnerability of elderly patients from various perspectives. The domains of the CGA include physical function, comorbidity, cognitive function, psychological status, social support system, nutrition, and medication. The CGA can be used to predict survival and adverse events; to identify health problems that cannot be detected based on medical history or examination; to recognize new problems that emerge during course observation; and to improve psychological conditions. However, application of the CGA in routine clinical practice requires establishment of a consensus regarding the survey method, evaluation scale, and use of results in decision-making. A prospective investigation of the CGA as an outcome index in elderly breast cancer patients is required to address these issues.

KW - ADL

KW - Breast cancer

KW - Comprehensive geriatric assessment (CGA)

KW - Elderly

KW - IADL

UR - http://www.scopus.com/inward/record.url?scp=77955501939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955501939&partnerID=8YFLogxK

U2 - 10.1007/s12282-009-0167-z

DO - 10.1007/s12282-009-0167-z

M3 - Article

C2 - 19756923

AN - SCOPUS:77955501939

VL - 17

SP - 183

EP - 189

JO - Breast Cancer

JF - Breast Cancer

SN - 1340-6868

IS - 3

ER -